From: How old is this mutation? - a study of three Ashkenazi Jewish founder mutations
Method | Estimated mutation age (generations) | Estimated mutation age including correction for growth with r = 1.125 | Estimated mutation age including correction for growth with r = 1.21 | 95% credible interval (DMLE) or 95% confidence interval |
---|---|---|---|---|
Estimate from Niell et al. (2003)[5] | 87.9 - 118 | Â | Â | Â |
Single marker - marker D5S1351,3 | 60.9 | 87.93 | 79.94 | Â |
Single marker - marker D5S3462,3 | 69.5 | 117.60 | 101.56 | Â |
DMLE | N/A | 105.76 | 69.16 | r = 1.21: [56.00, 83.22] r = 1.125: [85.96, 128.62] |
Goldgar method3 | 28 | 65.57 | 53.55 | r = 1.0: [20-39] r = 1.125: [57.57, 76.57] r = 1.21: [25.55, 64.55] |