IL10RA haplotype | Frequency | Â | Â | Â |
---|
 |  |  | MAP infection status |  |  |  |
---|
633C > A | 984G > A | 1185C > T | Negative (n = 235) | Positive (n = 180) | β ± SE | OR (95% CI) | Contrast ± SE |
---|
A | G | C | 52.6% | 60.6% | 0.35 ± 0.15 * | 1.42 (1.06-1.90) |  |
A | A | T | 27.2% | 20.8% | -0.37 ± 0.17 * | 0.69 (0.49-0.97) | -0.45 ± 0.18 ** |
C | A | C | 19.1% | 17.8% | -0.09 ± 0.18 | 0.92 (0.65-1.30) | -0.23 ± 0.19 |
A | A | C | 1.1% | 0.8% | -0.25 ± 0.74 | 0.78 (0.18-3.31) | -0.47 ± 0.74 |
- β ± SE, haplotype effect ± standard error; OR (95% CI), odds ratio (95% confidence interval); contrast ± SE, haplotype contrast ± standard error against the most frequent haplotype, AGC.
- * Comparison-wise significance at 5% probability level from logistic regression of haplotype counts against infection status.
- * * Experimental-wise significance at 5% probability level from logistic regression and Bonferroni's correction for multiple hypothesis testing.