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Table 3 Haplotype frequencies in the 3' coding region of IL10RA and their association with MAP-infection status.

From: Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status

IL10RA haplotype Frequency    
    MAP infection status    
633C > A 984G > A 1185C > T Negative (n = 235) Positive (n = 180) β ± SE OR (95% CI) Contrast ± SE
A G C 52.6% 60.6% 0.35 ± 0.15 * 1.42 (1.06-1.90)  
A A T 27.2% 20.8% -0.37 ± 0.17 * 0.69 (0.49-0.97) -0.45 ± 0.18 **
C A C 19.1% 17.8% -0.09 ± 0.18 0.92 (0.65-1.30) -0.23 ± 0.19
A A C 1.1% 0.8% -0.25 ± 0.74 0.78 (0.18-3.31) -0.47 ± 0.74
  1. β ± SE, haplotype effect ± standard error; OR (95% CI), odds ratio (95% confidence interval); contrast ± SE, haplotype contrast ± standard error against the most frequent haplotype, AGC.
  2. * Comparison-wise significance at 5% probability level from logistic regression of haplotype counts against infection status.
  3. * * Experimental-wise significance at 5% probability level from logistic regression and Bonferroni's correction for multiple hypothesis testing.