| |
Maximum incidence
|
Minimum incidence
|
Average
|
|---|
|
Type
|
freq. × 10-6
|
fraction
|
freq. × 10-6
|
fraction
|
×10-6
|
fraction
|
|---|
|
DMD/BMD
|
354
|
1/2825
|
186
|
1/5376
|
270
|
1/3703
|
|
Other dystrophies
|
100
|
1/10000
|
41
|
1/24390
|
70
|
1/14286
|
|
Congenital myopathies
|
219
|
1/4566
|
100
|
1/10000
|
160
|
1/6250
|
|
Total
|
673
|
1/1486
|
327
|
1/3050
|
500
|
1/2000
|
- DMD mean incidence is well established at 300 × 10-6 (Emery 2002) but data varies from country to country and survey to survey. It is unlikely to be much higher but may be as low as 169 × 10-6 (Cowan 1980). BMD frequency is based on (Emery 1991). Thankfully, both DMD and BMD incidence is probably declining annually due to genetic testing and counselling.
- Other dystrophy incidence numbers are scarce to non-existent. The rough estimate maximum is extrapolated from (Bushby 2001) and minimum from (Emery 2002).
- Other congenital myopathy numbers are also scarce to non-existent. The maximum estimate is extrapolated from (Nonaka 2001) as 81% of the mean DMD incidence. The minimum estimate is extrapolated from (D'Amico 2008) and (Lopate 2007).
- These data were used for estimation of testing cost and should be considered as rough estimates only.
