Figure 4From: Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalitiesSchematic diagram of recombinant chromosomes resulting from crossover between overlapping regions of Koa and Eh inversions. The Eh +/+ Koa double heterozygote has both Koa type and Eh type chromosomes. If crossover occurred in the overlapping region of the two inversions (C region), recombinant chromosomes with duplication of the B region and deletion of the D region (DupB-DelD), or with deletion of the B region and duplication of the D region (DelB-DupD), were transmitted to the offspring. The phenotypes of mice with these chromosomes are indicated at the bottom.Back to article page