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Complex traits and quantitative genetics

This section incorporates all aspects of complex trait and quantitative genetics including but not limited to: mapping and association studies, the genetic basis of disease, genetics aspects of breeding and linkage analysis.

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  1. The role of rhizosphere microbiome in supporting plant growth under biotic stress is well documented. Rhizobacteria ward off phytopathogens through various mechanisms including antibiosis. We sought to recover...

    Authors: Opeyemi K. Awolope, Noelle H. O’Driscoll, Alberto Di Salvo and Andrew J. Lamb

    Citation: BMC Genomic Data 2021 22:15

    Content type: Data note

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  2. Plant architecture-related traits (e.g., plant height (PH), number of nodes on main stem (NN), branch number (BN) and stem diameter (DI)) and 100-seed weight (100-SW) are important agronomic traits and are clo...

    Authors: Xiaoli Zhang, Wentao Ding, Dong Xue, Xiangnan Li, Yang Zhou, Jiacheng Shen, Jianying Feng, Na Guo, Lijuan Qiu, Han Xing and Jinming Zhao

    Citation: BMC Genomic Data 2021 22:10

    Content type: Research article

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  3. Multi-parent populations (MPPs) are important resources for studying plant genetic architecture and detecting quantitative trait loci (QTLs). In MPPs, the QTL effects can show various levels of allelic diversi...

    Authors: Vincent Garin, Valentin Wimmer, Dietrich Borchardt, Marcos Malosetti and Fred van Eeuwijk

    Citation: BMC Genomic Data 2021 22:4

    Content type: Research article

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  4. Recently, there has been a growing interest in the genetic improvement of body measurement traits in farm animals. They are widely used as predictors of performance, longevity, and production traits, and it is...

    Authors: Masoumeh Naserkheil, Deuk Hwan Lee and Hossein Mehrban

    Citation: BMC Genetics 2020 21:144

    Content type: Research article

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  6. Methane emission by ruminants has contributed considerably to the global warming and understanding the genomic architecture of methane production may help livestock producers to reduce the methane emission fro...

    Authors: Ali Jalil Sarghale, Mohammad Moradi Shahrebabak, Hossein Moradi Shahrebabak, Ardeshir Nejati Javaremi, Mahdi Saatchi, Majid Khansefid and Younes Miar

    Citation: BMC Genetics 2020 21:129

    Content type: Research article

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  7. The alteration in weather patterns expected due to climate change will affect farm animal performance, probably resulting in lower quantity and quality of available products. A potential mitigation strategy wo...

    Authors: Enrique Sánchez-Molano, Vanessa V. Kapsona, Stavroula Oikonomou, Ann McLaren, Nicola Lambe, Joanne Conington and Georgios Banos

    Citation: BMC Genetics 2020 21:116

    Content type: Research article

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  8. Feather pecking (FP) is damaging behavior in laying hens leading to global economic losses in the layer industry and massive impairments of animal welfare. The objective of the study was to discover genetic va...

    Authors: Clemens Falker-Gieske, Hanna Iffland, Siegfried Preuß, Werner Bessei, Cord Drögemüller, Jörn Bennewitz and Jens Tetens

    Citation: BMC Genetics 2020 21:114

    Content type: Research article

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  9. G-protein subunit beta 1 like (GNB1L) encodes a G-protein beta-subunit-like polypeptide. Chicken GNB1L is upregulated in the breast muscle of high feed efficiency chickens, and its expression is 1.52-fold that in...

    Authors: Tuanhui Ren, Ying Yang, Wujian Lin, Wangyu Li, Mingjian Xian, Rong Fu, Zihao Zhang, Guodong Mo, Wen Luo and Xiquan Zhang

    Citation: BMC Genetics 2020 21:91

    Content type: Research article

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  10. Both genetic and environmental factors contribute to type 2 diabetes development. We used consomic mice established from an animal type 2 diabetes model to identify susceptibility genes that contribute to type...

    Authors: Misato Kobayashi, Hironori Ueda, Naru Babaya, Michiko Itoi-Babaya, Shinsuke Noso, Tomomi Fujisawa, Fumihiko Horio and Hiroshi Ikegami

    Citation: BMC Genetics 2020 21:81

    Content type: Research article

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  11. Marek’s disease (MD) is a highly neoplastic disease primarily affecting chickens, and remains as a chronic infectious disease that threatens the poultry industry. Copy number variation (CNV) has been examined ...

    Authors: Hao Bai, Yanghua He, Yi Ding, Qin Chu, Ling Lian, Eliyahu M. Heifetz, Ning Yang, Hans H. Cheng, Huanmin Zhang, Jilan Chen and Jiuzhou Song

    Citation: BMC Genetics 2020 21:77

    Content type: Research article

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  12. Due to ethical reasons, surgical castration of young male piglets in their first week of life without anesthesia will be banned in Germany from 2021. Breeding against boar taint is already implemented in sire ...

    Authors: Ines Brinke, Christine Große-Brinkhaus, Katharina Roth, Maren J. Pröll-Cornelissen, Hubert Henne, Karl Schellander and Ernst Tholen

    Citation: BMC Genetics 2020 21:61

    Content type: Research article

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  13. Skin lesions and dermatoses in cattle are often associated with infections due to bacteria, fungi or environmental risk factors. Dermatoses with genetic etiology have been described in cattle. Among these rare...

    Authors: Irene M. Häfliger, Marlene Sickinger, Mark Holsteg, Leif M. Raeder, Manfred Henrich, Siegfried Marquardt, Cord Drögemüller and Gesine Lühken

    Citation: BMC Genetics 2020 21:55

    Content type: Research article

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  14. Ascites syndrome is a hypertensive, multifactorial, multigene trait affecting meat-type chickens imposing significant economic losses on the broiler industry. A region containing the CPQ gene has been previous...

    Authors: Alia Parveen, Christa D. Jackson, Shatovisha Dey, Katy Tarrant, Nicholas Anthony and Douglas D. Rhoads

    Citation: BMC Genetics 2020 21:54

    Content type: Research article

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  15. Tilapias (Family Cichlidae) are the second most important group of aquaculture species in the world. They have been the subject of much research on sex determination due to problems caused by early maturation ...

    Authors: Khanam Taslima, Stefanie Wehner, John B. Taggart, Hugues de Verdal, John A. H. Benzie, Michaël Bekaert, Brendan J. McAndrew and David J. Penman

    Citation: BMC Genetics 2020 21:49

    Content type: Research article

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  17. Body size traits as one of the main breeding selection criteria was widely used to monitor cattle growth and to evaluate the selection response. In this study, body size was defined as body height (BH), body l...

    Authors: Bingxing An, Lei Xu, Jiangwei Xia, Xiaoqiao Wang, Jian Miao, Tianpeng Chang, Meihua Song, Junqing Ni, Lingyang Xu, Lupei Zhang, Junya Li and Huijiang Gao

    Citation: BMC Genetics 2020 21:32

    Content type: Research article

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  18. Reproductive performance is critical for efficient swine production. Recent results indicated that vulva size (VS) may be predictive of reproductive performance in sows. Study objectives were to estimate genet...

    Authors: Flor-Anita Corredor, Leticia P. Sanglard, Richard J. Leach, Jason W. Ross, Aileen F. Keating and Nick V. L. Serão

    Citation: BMC Genetics 2020 21:28

    Content type: Research article

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  19. The diacylglycerol acyltransferases (DGAT) are a vital group of enzymes in catalyzing triacylglycerol biosynthesis. DGAT genes like DGAT1 and DGAT2, have been identified as two functional candidate genes affectin...

    Authors: Jiajia Liu, Zhiquan Wang, Jun Li, Hui Li and Liguo Yang

    Citation: BMC Genetics 2020 21:26

    Content type: Research article

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  20. Goats were domesticated 10,500 years ago to supply humans with useful resources. Since then, specialized breeds that are adapted to their local environment have been developed and display specific genetic prof...

    Authors: Estelle Talouarn, Philippe Bardou, Isabelle Palhière, Claire Oget, Virginie Clément, Gwenola Tosser-Klopp, Rachel Rupp and Christèle Robert-Granié

    Citation: BMC Genetics 2020 21:19

    Content type: Research article

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  21. Genomic evaluation, based on the use of thousands of genetic markers in addition to pedigree and phenotype information, has become the standard evaluation methodology in dairy cattle breeding programmes over t...

    Authors: David Picard Druet, Amandine Varenne, Florian Herry, Frédéric Hérault, Sophie Allais, Thierry Burlot and Pascale Le Roy

    Citation: BMC Genetics 2020 21:17

    Content type: Research Article

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  22. Quantitative traits are typically considered to be under additive genetic control. Although there are indications that non-additive factors have the potential to contribute to trait variation, experimental dem...

    Authors: Francois Besnier, Monica F. Solberg, Alison C. Harvey, Gary R. Carvalho, Dorte Bekkevold, Martin I. Taylor, Simon Creer, Einar E. Nielsen, Øystein Skaala, Fernando Ayllon, Geir Dahle and Kevin A. Glover

    Citation: BMC Genetics 2020 21:13

    Content type: Research article

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  23. Executive function (EF) is vital to human beings. It has been linked to many genes and family environmental factors in separate studies, but few studies have examined the potential interactions between gene(s)...

    Authors: Chunhui Chen, Chuansheng Chen, Gui Xue, Qi Dong, Libo Zhao and Shudong Zhang

    Citation: BMC Genetics 2020 21:11

    Content type: Research article

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  25. Anaerobic germination is one of the most important traits for rice under direct-seeded conditions. The trait reduces risk of crop failure due to waterlogged conditions after seeding and allows water to be used...

    Authors: Sharmistha Ghosal, Fergie Ann Quilloy, Carlos Casal Jr, Endang M. Septiningsih, Merlyn S. Mendioro and Shalabh Dixit

    Citation: BMC Genetics 2020 21:6

    Content type: Research article

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  26. Wheat mutant resources with phenotypic variation have been developed in recent years. These mutants might carry favorable mutation alleles, which have the potential to be utilized in the breeding process. Plan...

    Authors: Huijun Guo, Hongchun Xiong, Yongdun Xie, Linshu Zhao, Jiayu Gu, Shirong Zhao, Yuping Ding and Luxiang Liu

    Citation: BMC Genetics 2019 20:102

    Content type: Research article

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  27. Corin is an important convertase involved in the natriuretic peptide system and may indirectly regulate blood pressure. Genetic factors relate to corin remain unclear. The purpose of the current study was to c...

    Authors: Huan Zhang, Xingbo Mo, Qiyu Qian, Zhengyuan Zhou, Zhengbao Zhu, Xinfeng HuangFu, Tan Xu, Aili Wang, Zhirong Guo, Shufeng Lei and Yonghong Zhang

    Citation: BMC Genetics 2019 20:99

    Content type: Research article

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  28. Variants of the Ostreid herpesvirus 1 (OsHV-1) cause high losses of Pacific oysters globally, including in Tomales Bay, California, USA. A suite of new variants, the OsHV-1 microvariants (μvars), cause very high ...

    Authors: Konstantin Divilov, Blaine Schoolfield, Benjamin Morga, Lionel Dégremont, Colleen A. Burge, Daniel Mancilla Cortez, Carolyn S. Friedman, Gary B. Fleener, Brett R. Dumbauld and Chris Langdon

    Citation: BMC Genetics 2019 20:96

    Content type: Research article

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  29. Climate change is expected to have a negative impact on food availability. While most efforts have been directed to reducing greenhouse gas emissions, complementary strategies are necessary to control the detr...

    Authors: Enrique Sánchez-Molano, Vanessa V. Kapsona, Joanna J. Ilska, Suzanne Desire, Joanne Conington, Sebastian Mucha and Georgios Banos

    Citation: BMC Genetics 2019 20:84

    Content type: Research article

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  30. Feed efficiency and growth rate have been targets for selection to improve chicken production. The incorporation of genomic tools may help to accelerate selection. We genotyped 529 individuals using a high-den...

    Authors: Gabriel Costa Monteiro Moreira, Mirele Daiana Poleti, Fábio Pértille, Clarissa Boschiero, Aline Silva Mello Cesar, Thaís Fernanda Godoy, Mônica Corrêa Ledur, James M. Reecy, Dorian J. Garrick and Luiz Lehmann Coutinho

    Citation: BMC Genetics 2019 20:83

    Content type: Research article

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  31. Genomic selection has the potential to increase genetic gains by using molecular markers as predictors of breeding values of individuals. This study evaluated the accuracy of predictions for grain yield, headi...

    Authors: Dennis N. Lozada, R. Esten Mason, Jose Martin Sarinelli and Gina Brown-Guedira

    Citation: BMC Genetics 2019 20:82

    Content type: Research article

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  32. Kernel length (KL), kernel width (KW) and thousand-kernel weight (TKW) are key agronomic traits in wheat breeding. Chuannong16 (‘CN16’) is a commercial cultivar with significantly longer kernels than the line ...

    Authors: Jian Ma, Han Zhang, Shuiqin Li, Yaya Zou, Ting Li, Jiajun Liu, Puyang Ding, Yang Mu, Huaping Tang, Mei Deng, Yaxi Liu, Qiantao Jiang, Guoyue Chen, Houyang Kang, Wei Li, Zhien Pu…

    Citation: BMC Genetics 2019 20:77

    Content type: Research article

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  33. Arabian horses are commonly believed to be one of the oldest and the most popular horse breeds in the world, characterized by favourable stamina traits and exercise phenotypes. During intensive training, the r...

    Authors: Katarzyna Ropka-Molik, Monika Stefaniuk-Szmukier, Tomasz Szmatoła, Katarzyna Piórkowska and Monika Bugno-Poniewierska

    Citation: BMC Genetics 2019 20:73

    Content type: Research article

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  34. Yellow lupin (Lupinus luteus L.) is a promising grain legume for productive and sustainable crop rotations. It has the advantages of high tolerance to soil acidity and excellent seed quality, but its current yiel...

    Authors: Muhammad Munir Iqbal, Mark Huynh, Joshua A. Udall, Andrzej Kilian, Kedar N. Adhikari, Jens D. Berger, William Erskine and Matthew N. Nelson

    Citation: BMC Genetics 2019 20:68

    Content type: Research article

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  35. Fruit set after successful pollination is key for the production of sweet cherries, and a low fruit-setting rate is the main problem in production of this crop. As gibberellin treatment can directly induce par...

    Authors: Binbin Wen, Wenliang Song, Mingyue Sun, Min Chen, Qin Mu, Xinhao Zhang, Qijie Wu, Xiude Chen, Dongsheng Gao and Hongyu Wu

    Citation: BMC Genetics 2019 20:65

    Content type: Research article

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  36. Apogamy is a unique asexual reproduction in the ferns, in which somatic cells of gametophytes go through dedifferentiation and then differentiate into haploid sporophytes bypassing fertilization. Restricted to...

    Authors: Qi Fu and Long-qing Chen

    Citation: BMC Genetics 2019 20:55

    Content type: Research article

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  37. Fusarium head blight (FHB) is a problem of great concern in small grain cereals, especially wheat. A quantitative trait locus (QTL) for FHB resistance (FHB_SFI) located on the long arm of chromosome 2D in the spr...

    Authors: Xinkun Hu, Hélène Rocheleau, Curt McCartney, Chiara Biselli, Paolo Bagnaresi, Margaret Balcerzak, George Fedak, Zehong Yan, Giampiero Valè, Shahrokh Khanizadeh and Thérèse Ouellet

    Citation: BMC Genetics 2019 20:47

    Content type: Research article

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    The Correction to this article has been published in BMC Genetics 2019 20:76

  38. The 100-pod fresh weight (PFW), 100-seed fresh weight (SFW), 100-seed dry weight (SDW) and moisture content of fresh seeds (MCFS) at the R6 stage are crucial factors for vegetable soybean yield. However, the g...

    Authors: Xiangnan Li, Xiaoli Zhang, Longming Zhu, Yuanpeng Bu, Xinfang Wang, Xing Zhang, Yang Zhou, Xiaoting Wang, Na Guo, Lijuan Qiu, Jinming Zhao and Han Xing

    Citation: BMC Genetics 2019 20:39

    Content type: Research article

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  39. Aflatoxin contamination caused by Aspergillus flavus is a major constraint to peanut industry worldwide due to its toxicological effects to human and animals. Developing peanut varieties with resistance to seed i...

    Authors: Bolun Yu, Dongxin Huai, Li Huang, Yanping Kang, Xiaoping Ren, Yuning Chen, Xiaojing Zhou, Huaiyong Luo, Nian Liu, Weigang Chen, Yong Lei, Manish K. Pandey, Hari Sudini, Rajeev K. Varshney, Boshou Liao and Huifang Jiang

    Citation: BMC Genetics 2019 20:32

    Content type: Research article

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  40. A genome-wide mapping study using male F2 zinc transporter 7-knockout mice (znt7-KO) and their wild type littermates in a mixed 129P1/ReJ (129P1) and C57BL/6J (B6) background identified a quantitative trait locus...

    Authors: L. Huang, S. Tepaamorndech, C. P. Kirschke, Y. Cai, J. Zhao, Xiaohan Cao and Andrew Rao

    Citation: BMC Genetics 2019 20:19

    Content type: Research article

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  41. Genome-wide association studies (GWAS) have been successfully implemented in cattle research and breeding. However, moving from the associations to identify the causal variants and reveal underlying mechanisms...

    Authors: Zexi Cai, Bernt Guldbrandtsen, Mogens Sandø Lund and Goutam Sahana

    Citation: BMC Genetics 2019 20:15

    Content type: Methodology article

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  42. Traditional single nucleotide polymorphism (SNP) genome-wide association analysis (GWAA) can be inefficient because single SNPs provide limited genetic information about genomic regions. On the other hand, usi...

    Authors: Camila U. Braz, Jeremy F. Taylor, Tiago Bresolin, Rafael Espigolan, Fabieli L. B. Feitosa, Roberto Carvalheiro, Fernando Baldi, Lucia G. de Albuquerque and Henrique N. de Oliveira

    Citation: BMC Genetics 2019 20:8

    Content type: Research article

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  43. Bovine respiratory disease complex (BRDC) is one of the most important sources of loss within the beef cattle industry in the USA. Steps have been taken to reduce the incidence of BRDC through vaccination. Des...

    Authors: L. M. Kramer, M. S. Mayes, E. D. Downey, R. G. Tait Jr, A. Woolums, C. Chase and J. M. Reecy

    Citation: BMC Genetics 2019 20:6

    Content type: Research article

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  44. The number of animals born dead, which includes the number of mummified (NM) and stillborn (NS) animals, is the most important trait to directly quantify the reproductive loss in domestic pigs. In this study, ...

    Authors: Pingxian Wu, Kai Wang, Jie Zhou, Qiang Yang, Xidi Yang, Anan Jiang, Yanzhi Jiang, Mingzhou Li, Li Zhu, Lin Bai, Xuewei Li and Guoqing Tang

    Citation: BMC Genetics 2019 20:4

    Content type: Research article

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  45. Erythropoietin receptor (EPOR) is a functional membrane-bound cytokine receptor. Erythropoietin (EPO) represents an important hematopoietic factor for production, maturation and differentiation of erythroid pr...

    Authors: Barbora Fecková, Patrícia Kimáková, Lenka Ilkovičová, Erika Szentpéteriová, Mária Macejová, Ján Košuth, Anthony Zulli, Nataša Debeljak, Petra Hudler, Karin Jašek, Ivana Kašubová, Peter Kubatka and Peter Solár

    Citation: BMC Genetics 2019 20:1

    Content type: Research article

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  46. In our previous genome-wide association study (GWAS) on the piglet splay leg (PSL) syndrome, the homer scaffolding protein 1 (HOMER1) was detected as a candidate gene. The aim of this work was to further verify t...

    Authors: Sutong Xu, Xingjie Hao, Min Zhang, Kai Wang, Shuaifeng Li, Xing Chen, Liaohan Yang, Lin Hu and Shujun Zhang

    Citation: BMC Genetics 2018 19:110

    Content type: Research article

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  47. The main goal of selection is to achieve genetic gain for a population by choosing the best breeders among a set of selection candidates. Since 2013, the use of a high density genotyping chip (600K Affymetrix®...

    Authors: Florian Herry, Frédéric Hérault, David Picard Druet, Amandine Varenne, Thierry Burlot, Pascale Le Roy and Sophie Allais

    Citation: BMC Genetics 2018 19:108

    Content type: Research article

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  48. Improving feed efficiency in fish is crucial at the economic, social and environmental levels with respect to developing a more sustainable aquaculture. The important contribution of genetic improvement to ach...

    Authors: Hugues de Verdal, Marc Vandeputte, Wagdy Mekkawy, Béatrice Chatain and John A. H. Benzie

    Citation: BMC Genetics 2018 19:105

    Content type: Research article

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  49. Identification of genes underlying production traits is a key aim of the mink research community. Recent availability of genomic tools have opened the possibility for faster genetic progress in mink breeding. ...

    Authors: Zexi Cai, Trine Michelle Villumsen, Torben Asp, Bernt Guldbrandtsen, Goutam Sahana and Mogens Sandø Lund

    Citation: BMC Genetics 2018 19:103

    Content type: Research article

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  50. Congenital skeletal malformations represent a heterogeneous group of disorders affecting bone and cartilage development. In cattle, particular chondrodysplastic forms have been identified in several miniature ...

    Authors: Ann-Kathrin Struck, Claudia Dierks, Marina Braun, Maren Hellige, Anna Wagner, Bernd Oelmaier, Andreas Beineke, Julia Metzger and Ottmar Distl

    Citation: BMC Genetics 2018 19:91

    Content type: Research article

    Published on:

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