Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study

Table 2 The results of causal analysis of human blood metabolites (exposure) and pulmonary embolism (outcome)

Exposure group	Number of SNP	Analytical method	Beta	SE	95%CI	P
1-stearoylglycerophosphoethanolamine	1	Wald ratio	−0.009597	0.007869	(−0.0250, 0.0059)	0.2226
X-12100--hydroxytryptophan	2	IVW	−0.0294	0.01056	(−0.0087, − 0.0500)	0.005349
X-11412	1	Wald ratio	−0.01947	0.0178	(−0.0543,0.0154)	0.274
X-12029	1		NA
N1-methyladenosine	1	Wald ratio	−0.006814	0.0306	(−0.0668,0.0532	0.8238
valine	1	Wald ratio	−0.02911	0.02328	(−0.0747,0.0165	0.211

Tests were considered statistically significant at P values < 0.05. The MR base platform (http://app.mrbase.org/) was used for MR analyses

ISSN: 2730-6844