Fig. 1

Interface of the web application. A typical search starts with inserting an identifier in the first window of “Search Options”, either Entrez Gene ID (e.g., “1234”), an Accession Number (e.g., “BE644809” or “NM_005715”), a Gene Symbol (e.g., “NR3C1” or “CREB1”, not case-sensitive) or an Affymetrix probe set ID (e.g., “8,114,814”). Then, a specific transcript can be traced by inserting a second identifier in window two under “Search Options”. Alternatively, the window may be left open to obtain a list of the transcripts most significantly correlating to the identifier in the first window. Filling in boxes in the “Output Options” fields enables restriction of output to e.g., transcripts having specific keywords in Gene Ontology (GO), TFs (genes having “transcription” as part of the Gene Title) or only positive or negative correlations