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Fig. 3 | BMC Genomic Data

Fig. 3

From: Identification of hub genes and pathways in colitis-associated colon cancer by integrated bioinformatic analysis

Fig. 3

Protein–protein network and module analysis of DEGs. The network map of DEGs was constructed using STRING (a). The modular analysis was carried out on the network to screen out the module (b) with the highest score (MCODE score = 9.0). Red represents upregulated genes and the blue represents downregulated genes. Gene ontology (GO) enrichment analysis in DEGs and module genes were performed using the DAVID Database (c: DEGs, d: module genes); Classification: Biological Process (BP), B: Cellular Component (CC), C: Molecular Function (MF). KEGG pathways using the ggplot2 package in R language for visualization (e: DEGs, f: module genes). The size of the dot represents the amount of gene enrichment, and the color of the dot represents p value

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BMC Genomic Data

ISSN: 2730-6844

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