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Table 1 Basic clinical characteristics and subgroup frequencies of CYB5Aalt positive and negative patients in cohort 1

From: An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse

 

CYB5Aalt-status

positive (n = 9)

negative (n = 41)

median BM blast count (%) at ID

88

92

median age at ID (years)

18

15

median time to REL (days)

615

744

samples

 adult (n = 24)

5

19

 pediatric (n = 26)

4

22

sex

 male (n = 27)

4

23

 female (n = 23)

5

18

molecular subgroup

 NH (n = 4)

2

2

 HeH (n = 6)

3

3

 LH (n = 4)

1

3

 Ph-like (n = 12)

1

11

 DUX4r (n = 12)

0

12

 Unknown (n = 3)

0

3

 BCL2r (n = 2)

0

2

 PAX5mut (n = 2)

0

2

 PAX5r (n = 1)

0

1

 MEF2Dr (n = 1)

0

1

 MLLr (n = 2)

0

2

 ZNF384f (n = 2)

0

2

  1. Table 1 lists a comparison of characteristics for CYB5Aalt positive patients (n = 9) and negative patients (n = 41) in cohort 1 (n = 50). Characteristics include median bone marrow (BM) blast count, age, sex, frequencies of adult (n = 24) and pediatric patients (n = 26) and median time to REL. Further, frequencies of CYB5Aalt-positive and negative samples in the different molecular subtypes in cohort 1 are listed with total number of patients per subgroup in brackets, respectively