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Table 3 Association of the hub genes with immune cells in the GEO GSE7305, GSE7307, and GSE11691 datasets

From: Bioinformatical analysis of the key differentially expressed genes and associations with immune cell infiltration in development of endometriosis

cell

HUB genes

IL6

FN1

R

P value

R

P value

CD4 + T-cells

-0.326475156

0.00332006

0.300191272

0.007189741

CD8 + T-cells

/

/

0.434110165

6.41E-05

CD8 + Tem

/

/

0.684326393

3.58E-12

Memory B-cells

-0.514066535

1.26E-06

0.571878555

3.69E-08

Eosinophils

/

/

0.567365684

4.98E-08

Monocytes

/

/

0.710500128

2.23E-13

Th1 cells

/

/

0.626348779

6.67E-10

aDC

0.695185664

1.17413E-12

/

/

pDC

/

/

0.458398123

2.15E-05

cell

CDH1

 

CXCL8

 
 

R

P value

R

P value

CD4 + T-cells

0.440221026

4.91E-05

/

/

CD8 + T-cells

0.431511911

7.17E-05

0.265114523

0.018213423

CD8 + Tem

/

/

/

/

Memory B-cells

/

/

-0.279451283

0.012626547

Eosinophils

/

/

/

/

Monocytes

/

/

/

/

Th1 cells

-0.297525423

0.007746875

0.31216276

0.00509934

aDC

/

/

0.710995393

2.11E-13

pDC

/

/

0.311325106

0.005225759

cell

IGF1

 

CDK1

 
 

R

P value

R

P value

CD4 + T-cells

0.640627142

2.04E-10

0.23983578

0.033261958

CD8 + T-cells

0.602311076

4.30E-09

/

/

CD8 + Tem

/

/

-0.430468068

7.50E-05

Memory B-cells

0.338145051

0.002304351

-0.447874672

3.49E-05

Eosinophils

0.44016858

4.92E-05

/

/

Monocytes

0.530834902

4.84E-07

/

/

Th1 cells

/

/

-0.468975666

1.30E-05

aDC

/

/

0.239747929

0.033328496

pDC

0.272858276

0.01497764

/

/

cell

PTPRC

 

CCNB1

 
 

R

P value

R

P value

CD4 + T-cells

/

/

/

/

CD8 + T-cells

0.399004506

0.000270095

/

/

CD8 + Tem

0.515246752

1.18E-06

-0.50319671

2.28E-06

Memory B-cells

/

/

-0.485778005

5.68E-06

Eosinophils

/

/

-0.294015063

0.008538147

Monocytes

0.441980272

4.54E-05

/

/

Th1 cells

0.503419828

2.26E-06

-0.548790451

1.64E-07

aDC

0.648547555

1.03E-10

/

/

pDC

0.376824412

0.00061932

/

/

cell

MKI67

 

ESR1

 
 

R

P value

R

P value

CD4 + T-cells

/

/

0.552859509

1.27E-07

CD8 + T-cells

/

/

0.403979285

0.000222414

CD8 + Tem

-0.457126222

2.29E-05

/

/

Memory B-cells

-0.57766168

2.49E-08

0.271533729

0.015493073

Eosinophils

-0.33723805

0.002371882

0.297309918

0.007793527

Monocytes

/

/

0.271319599

0.015577821

Th1 cells

-0.515808407

1.14E-06

-0.335833915

0.002479934

aDC

0.343556969

0.00193608

-0.321253615

0.003891915

pDC

/

/

/

/

  1. R represents the Pearson correlation coefficient value; / indicates that the p value is greater than 0.05, which is not statistically significant