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Fig. 8 | BMC Genomic Data

Fig. 8

From: Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

Fig. 8

Schematic representation of topologically associating domains (TADs). Red stars are SNPs highly associated with a disease at a p-value of ≤5 × 10− 8, orange rounded squares represent enhancers, green circles represent transcription factors, and blue square brackets show the location of TAD boundaries. TADs are divided into two groups, A control TADs containing no highly associated SNPs and B SNP-rich TADs carrying at least one highly associated variant

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BMC Genomic Data

ISSN: 2730-6844

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