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Fig. 4 | BMC Genomic Data

Fig. 4

From: Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

Fig. 4

Analysis of the disease association of transcription factors (TFs) linked to SNPs. A The distribution of disease-association (DA) scores for TFs linked to SNPs highly associated with breast cancer. B The fraction of disease-associated TFs linked to SNPs highly associated with prostate cancer. TFs were identified by mapping SNPs in the unidimensional (1D, purple violins) and the three-dimensional (3D, yellow violins) genome structure. In each violin, the horizontal black line is the median, the narrow gray box shows the first and third quantiles, and whiskers mark the minimum and maximum values excluding outliers, which are represented by black diamonds

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