Fig. 3From: The mtDNA mutation spectrum in the PolG mutator mouse reveals germline and somatic selectionA. The mean mutation frequency is plotted across the entire mtDNA genome. Frequencies were averaged if more than one mutation appeared in one base pair. Normalized values were found using {(x/max(x))}. Lines show the rolling mean (250 bp) of both the frequency and count. Mutation Count, B, C. and Mutation Frequency, D, E. are shown for protein coding (CDS), tRNA, rRNA, and D-loop regions. Mutation count and frequency are normalized to region length. N = 14. Error bars are ±95% CI, black dots represent the medianBack to article page