Associations between polymorphisms of SLC22A7, NGFR, ARNTL and PPP2R2B genes and Milk production traits in Chinese Holstein

Table 2 Transcription factor binding sites (TFBSs) prediction for NGFR and ARNTL genes

Gene	SNPs	Allele	Transcription factor	Relative score (≥0.80)	Predicted binding site sequence
NGFR	19:g.37113872C > G	C	SNAI2	0.86	CACAAGTAT
		G	SPI1	0.87	CAGAAG
		G	OSR2	0.90	TAACAGAAGTAT
	19:g.37113157C > T	T	STAT3	0.86	GGTCCTGGAAA
			FEV	0.88	CTGGAAAT
			ETV6	0.85	CCTGGAAATG
		C	GATA2	0.94	AGATG
		C	GATA1	0.93	AGATGT
	19:g.37112276C > T	T	MXI1	0.90	GGCACACGGG
		C	NRF1	0.85	GCGCACGGGCG
		C	SOHLH2	0.85	CGCACGGGCG
ARNTL	15:g.39320936A > G	G	DMRTA2	0.82	GTGTGCTACAGG
			OSR1	0.82	TGCTACAGGG
			PAX5	0.80	GTGTGCTACAGGGTGGGAA
			TFAP2C	0.80	TGCTACAGGGT
		A	FOXL1	0.82	GTGCTATA
			HOXC8	0.80	GCTATAGG
			MZF1	0.80	ATAGGGTGGG
			TBX6	0.80	AGTGTGCTAT

ISSN: 2730-6844