Fig. 5

Gene expression functional in NETosis is negatively correlated with oxygen saturation in severe COVID-19 illness. Temporal line plots of selected NETosis genes in the severe patient (Case 1) over days of illness. Each plot corresponds to one gene, with the red line representing oxygen saturation (%), and the blue line representing level of gene expression. Pearson correlation coefficient (r) is negative between oxygen saturation and level of expression of these genes. In contrast to other genes shown here, CEACAM8 up-regulation is sustained over time. Gene expression data were extracted from [13]