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Fig. 3 | BMC Genomic Data

Fig. 3

From: Identification of common microRNA between COPD and non-small cell lung cancer through pathway enrichment analysis

Fig. 3

Results of miRNA set enrichment analysis in COPD and NSCLC for non-small cell lung cancer, cell cycle, and p53 signaling pathways. MiRSEA performs differential expression analysis for miRNAs based on differential weighted scores (a); integrates the differential expression level of miRNAs and miRNA-pathway weights, calculates miRScore, and creates a ranked list of miRNAs. Then, it maps miRNAs in the pathway to the ranked list and calculates the miRNA enrichment score for each pathway and miRNA correlation profiles (b); after calculating the enrichment score, MiRSEA prioritizes a pathway by FDR and the running miRNAs enrichment score for the pathway results (c)

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BMC Genomic Data

ISSN: 2730-6844

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