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Table 4 Estimated median of the point estimates of γ, CP (in %), ML (in %), MR (in %), Ratio (ML/(ML + MR)), DP (in %) and EP (in %) of two-sided 95% CIs of γ for the LR, Fieller’s and delta methods against γ, with a = 0.1 and 0.3, p = 0.1 and 0.3, n = 2,000 and ρ = 0 based on 10,000 replicates

From: A statistical measure for the skewness of X chromosome inactivation for quantitative traits and its application to the MCTFR data

    

LR

Fieller

Deltaa

a

p

γ

Median

CP

ML

MR

Ratio

DP

EP

CP

ML

MR

Ratio

DP

EP

CP

ML

MR

Ratio

0.1

0.1

0

0.00

94.78

2.70

0.00

1.00

1.22

2.16

94.90

2.60

0.00

1.00

1.12

2.13

99.36

0.64

0.00

1.00

0.1

0.1

0.5

0.49

94.94

2.17

2.68

0.45

0.00

0.00

95.01

2.12

2.69

0.44

0.00

0.00

93.57

0.00

6.43

0.00

0.1

0.1

1

1.00

95.07

2.12

2.40

0.47

0.00

0.05

95.03

2.13

2.42

0.47

0.00

0.07

91.37

0.00

8.63

0.00

0.1

0.1

1.5

1.48

94.95

1.89

2.56

0.42

0.00

0.44

94.97

1.91

2.52

0.43

0.00

0.44

90.72

0.00

9.28

0.00

0.1

0.1

2

1.99

95.07

0.00

2.61

0.00

0.00

2.31

95.08

0.00

2.63

0.00

0.00

2.29

90.50

0.00

9.50

0.00

0.1

0.3

0

0.00

95.15

2.40

0.00

1.00

0.00

2.44

95.05

2.46

0.00

1.00

0.00

2.49

97.12

2.88

0.00

1.00

0.1

0.3

0.5

0.50

94.83

2.61

2.56

0.50

0.00

0.00

94.86

2.56

2.58

0.50

0.00

0.00

95.65

1.68

2.67

0.39

0.1

0.3

1

1.00

95.18

2.46

2.34

0.51

0.00

0.00

95.20

2.47

2.33

0.51

0.00

0.00

95.86

0.54

3.60

0.13

0.1

0.3

1.5

1.50

94.66

2.65

2.69

0.50

0.00

0.00

94.70

2.65

2.65

0.50

0.00

0.00

95.50

0.00

4.50

0.00

0.1

0.3

2

2.00

94.90

0.00

2.47

0.00

0.00

2.62

94.88

0.00

2.49

0.00

0.00

2.63

95.31

0.00

4.69

0.00

0.3

0.1

0

0.00

94.70

2.88

0.00

1.00

0.98

2.01

94.79

2.83

0.00

1.00

1.01

1.99

99.43

0.57

0.00

1.00

0.3

0.1

0.5

0.49

94.79

2.45

2.53

0.49

0.00

0.00

94.69

2.45

2.55

0.49

0.00

0.00

93.73

0.00

6.27

0.00

0.3

0.1

1

0.99

94.89

2.05

2.50

0.45

0.00

0.10

94.95

2.03

2.46

0.45

0.00

0.10

91.56

0.00

8.44

0.00

0.3

0.1

1.5

1.50

95.03

1.80

2.50

0.42

0.00

0.37

95.09

1.78

2.47

0.42

0.00

0.37

91.16

0.00

8.84

0.00

0.3

0.1

2

1.98

95.17

0.00

2.28

0.00

0.00

2.55

95.17

0.00

2.25

0.00

0.00

2.58

90.80

0.00

9.20

0.00

0.3

0.3

0

0.00

94.85

2.50

0.00

1.00

0.00

2.61

94.82

2.56

0.00

1.00

0.00

2.62

97.03

2.97

0.00

1.00

0.3

0.3

0.5

0.50

95.16

2.38

2.17

0.52

0.00

0.00

95.11

2.42

2.17

0.53

0.00

0.00

96.21

1.56

2.23

0.41

0.3

0.3

1

1.00

94.98

2.47

2.55

0.49

0.00

0.00

94.99

2.45

2.56

0.49

0.00

0.00

95.66

0.66

3.68

0.15

0.3

0.3

1.5

1.50

94.76

2.68

2.56

0.51

0.00

0.00

94.78

2.70

2.52

0.52

0.00

0.00

95.48

0.00

4.52

0.00

0.3

0.3

2

2.00

94.80

0.00

2.55

0.00

0.00

2.65

94.79

0.00

2.55

0.00

0.00

2.66

95.19

0.00

4.81

0.00

  1. a DP and EP of the delta method are zero