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Table 2 Estimated sizes (in %) for testing H0 : γ = γ0 for the LR, Fieller’s and delta methods with a = 0.1 and 0.3, p = 0.1 and 0.3, n = 2,000 and ρ = 0 based on 10,000 replicates and 5% significance level

From: A statistical measure for the skewness of X chromosome inactivation for quantitative traits and its application to the MCTFR data

a

p

γ0

LR

Fieller

Delta

0.1

0.1

0

5.22

5.10

0.64

0.1

0.1

0.5

5.06

4.99

6.43

0.1

0.1

1

4.93

4.97

8.63

0.1

0.1

1.5

5.05

5.03

9.28

0.1

0.1

2

4.93

4.92

9.50

0.1

0.3

0

4.85

4.95

2.88

0.1

0.3

0.5

5.17

5.14

4.35

0.1

0.3

1

4.82

4.80

4.14

0.1

0.3

1.5

5.34

5.30

4.50

0.1

0.3

2

5.10

5.12

4.69

0.3

0.1

0

5.30

5.21

0.57

0.3

0.1

0.5

5.21

5.31

6.27

0.3

0.1

1

5.11

5.05

8.44

0.3

0.1

1.5

4.97

4.91

8.84

0.3

0.1

2

4.83

4.83

9.20

0.3

0.3

0

5.15

5.18

2.97

0.3

0.3

0.5

4.84

4.89

3.79

0.3

0.3

1

5.02

5.01

4.34

0.3

0.3

1.5

5.24

5.22

4.52

0.3

0.3

2

5.20

5.21

4.81