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Table 1 Estimated sizes (in %) for testing H0 : γ = γ0 for the LR, Fieller’s and delta methods with a = 0.1 and 0.3, p = 0.1 and 0.3, n = 1,000 and ρ = 0 based on 10,000 replicates and 5% significance level

From: A statistical measure for the skewness of X chromosome inactivation for quantitative traits and its application to the MCTFR data

a

p

γ0

LR

Fieller

Delta

0.1

0.1

0

4.96

4.87

0.24

0.1

0.1

0.5

5.11

5.00

6.24

0.1

0.1

1

4.89

4.80

10.27

0.1

0.1

1.5

5.30

5.23

11.13

0.1

0.1

2

4.96

4.98

11.16

0.1

0.3

0

4.92

4.90

2.86

0.1

0.3

0.5

5.29

5.24

3.13

0.1

0.3

1

4.71

4.74

3.77

0.1

0.3

1.5

5.19

5.02

5.15

0.1

0.3

2

5.02

4.90

5.47

0.3

0.1

0

5.10

5.07

0.26

0.3

0.1

0.5

5.05

5.05

5.73

0.3

0.1

1

5.04

5.00

10.33

0.3

0.1

1.5

5.09

5.07

11.51

0.3

0.1

2

5.13

5.19

11.34

0.3

0.3

0

4.94

4.85

2.79

0.3

0.3

0.5

4.91

4.92

2.90

0.3

0.3

1

5.24

5.23

4.46

0.3

0.3

1.5

5.07

5.05

5.05

0.3

0.3

2

4.82

4.89

5.12