Transcriptome signature of miRNA-26b KO mouse model suggests novel targets

BMC Genomic Data

Table 4 Overview of leukocyte subsets in the spleen

Spleen	*MiRNA-26b*^+/+	*MiRNA-26b*^−/−	*P-value*
Neutrophils [× 10⁵/Spleen]	11.9 ± 1.0	9.0 ± 0.7	0.028
Classical Monocytes [× 10⁵/Spleen]	1.1 ± 0.2	1.0 ± 0.2	0.757
Non-classical Monocytes [× 10⁴/Spleen]	6.5 ± 0.5	18.2 ± 2.6	< 0.0001
B cells [× 10⁶/Spleen]	6.2 ± 0.5	6.6 ± 0.5	0.531
CD3⁺ T cells [× 10⁶/Spleen]	2.7 ± 0.2	3.1 ± 0.2	0.294
CD4⁺ T cells [× 10⁵/Spleen]	5.6 ± 0.3	6.6 ± 0.7	0.239
CD8⁺ T cells [× 10⁶/Spleen]	1.7 ± 0.1	2.1 ± 0.2	0.084

Values (n = 10–11) indicate total cell counts per spleen, denoted as mean ± SEM, as analyzed by Student t-test/Welch correction or Mann-Whitney test, depending on D’Agostino-Pearson normality testing

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