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Fig. 7 | BMC Genomic Data

Fig. 7

From: Transcriptome signature of miRNA-26b KO mouse model suggests novel targets

Fig. 7

miRNA-26b−/− differentially influences predicted miRNA-26b target genes. a ‘Volcano plot’ of miRNA-26b target score (mmu-miRNA-26b target score) against fold change (Fc) between miRNA-26b−/− and miRNA-26b+/+ mice, demonstrating the most significantly influenced target genes from miRNA-26b−/−. Every target gene is represented by a single dot. Significant but not differentially expressed genes are visualized in gray, significantly down-regulated genes in blue, significantly upregulated gene in red, significantly downregulated genes with high target score in black and significantly upregulated genes with high target score in gold. Mmu-miRNA-26b target score cut-off was set at 50 and Fc at − 1.5 or 1.5. b Relative mRNA expression measured by real time PCR. Data represent mean ± SEM, as analyzed by Mann-Whitney test

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