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Table 4 Candidate genes in the selection regions and their functions

From: Analysis of selection signatures on the Z chromosome of bidirectional selection broiler lines for the assessment of abdominal fat content

Gene symbol

Location (Mb)

Full name

Function of association

FGF10

13.97–14.03

Fibroblast growth factor 10

Promotes fat formation [22]

IL6ST

17.02–17.06

Interleukin 6 signal transducer

Increases fat oxidation and fatty acid re-esterification [25].

ELOVL7

18.87–18.91

ELOVL fatty acid elongase 7

Extension of saturated fatty acids [26]

IQGAP2

23.46–23.58

IQ motif containing GTPase activating protein 2

Influences the liver uptake of free fatty acids, fatty acid synthesis and adipogenesis [27]

CKMT2

63.95–63.98

Creatine kinase, mitochondrial 2

Regulation of energy metabolism, expression in brown adipose tissue [28]

PAX5

82.01–82.12

Paired box 5

Regulates obesity [29]