Table 2 Summary of the meta-analysis of the association of APOA gene polymorphisms with hyperlipidemia

APOA5–1131 T>C

A

C vs T

73.9%/ < 0.001

1.996(1.529 ~ 2.606)

< 0.001

0.353

D

TC + CC vs TT

71.2%/ < 0.001

2.179(1.565 ~ 3.035)

< 0.001

0.258

R

CC vs TC + TT

5.5%/ 0.390

2.790(2.055 ~ 3.789)

< 0.001

0.991

C

CC vs TT

45.7%/ 0.056

3.604(2.589 ~ 5.017)

< 0.001

0.899

TC vs TT

67.2%/ 0.001

1.932(1.395 ~ 2.674)

< 0.001

0.465

APOA1-75 bp

A

A vs G

1.2%/ 0.400

1.228(1.067 ~ 1.413)

0.004

0.086

D

AA+GA vs GG

0.0%/ 0.704

1.246(1.056 ~ 1.471)

0.009

0.067

R

AA vs GA + GG

15.9%/ 0.313

1.458(0.976 ~ 2.180)

0.066

0.086

C

AA vs GG

17.4%/ 0.304

1.520(1.008 ~ 2.291)

0.046

0.086

GA vs GG

0.0%/ 0.828

1.212(1.020 ~ 1.439)

0.029

0.221

APOA1 + 83 bp

A

T vs C

0.0%/ 0.472

0.928(0.771 ~ 1.116)

0.425

0.440

D

TT + TC vs CC

0.0%/ 0.478

0.950(0.780 ~ 1.157)

0.607

0.371

R

TT vs TC + CC

0.0%/ 0.799

0.310(0.076 ~ 1.271)

0.104

0.315

C

TT vs CC

0.0%/ 0.775

0.308(0.075 ~ 1.259)

0.101

0.346

TC vs CC

0.0%/ 0.607

0.967(0.793 ~ 1.180)

0.740

0.466