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Table 4 Candidate genes and previously identified related QTL for genomic regions associated with vulva size traits

From: Genetic and genomic characterization of vulva size traits in Yorkshire and Landrace gilts

BreedTraitaSSCbMbcCandidate genesRelated QTL
LandraceVA, VH, VW2154–157PDGFRB, MGAT1Total number born, corpus luteum number [7], gestation length, mummified pigs [8].
 VA, VH7107–110FLRT2, SPATA7, TGFB3, IRF2BPLTeat number [9,10,11,12], uterine horn length [13], nonfunctional nipples [14].
 VA, VW84–6MAN2B2Corpus luteum number [7, 15, 16], total number born alive, total number born [17], nonfunctional nipples [18], cryptorchidism [19], plasma FSH concentration [20], teat number [21].
 VA, VH108–19ESRRG, TGFB2Number of stillborn [8], corpus luteum number [7], teat number [9].
YorkshireVH187–91FYN, TSPYL1, TSPYL4Teat number [9, 22], total number born alive [8, 23], total number born, litter weight [23], mummified pigs [8].
 VA, VH, VW1282–287ACTL7A, ACTL7B, CTNNAL1, PTGR1Total number born, mummified pigs [8], teat number [9, 22, 24], age at puberty [10], left teat number, right teat number [22], corpus luteum number [7].
 VH567CD9, GAPDH, AKAP3Teat number [17], uterine horn weight, reproductive tract weight, uterine horn length [25], corpus luteum number [7], litter weight [23].
  1. aVA vulva area, VH vulva height, VW vulva width;
  2. bSus scrofa chromosome;
  3. cMegabase location of the SNP window