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Table 3 Correlation matrix of the CpG locus in the region of chicken KLF7

From: DNA methylation of CpG sites in the chicken KLF7 promoter and Exon 2 in association with mRNA expression in abdominal adipose tissue and blood metabolic indicators

 

E2CpG2

E2CpG3

E2CpG4

E2CpG5

E2CpG6–7

E2CpG8

E2CpG9

E2CpG10

E2CpG11–12

E2CpG13

E2CpG14

E2CpG3

1.0000 a

          

<.0001 b

          

19 c

          

E2CpG4

0.2938

0.2938

         

0.2221

0.2221

         

19

19

         

E2CpG5

0.0197

0.0197

0.0859

        

0.9380

0.9380

0.7187

        

18

18

20

        

E2CpG67

0.2824

0.2824

−0.3787

−0.0197

       

0.2414

0.2414

0.0905

0.9342

       

19

19

21

20

       

E2CpG8

0.0366

0.0366

0.2197

0.2710

0.2730

      

0.8854

0.8854

0.3520

0.2618

0.2442

      

18

18

20

19

20

      

E2CpG9

−0.1636

− 0.1636

− 0.0599

0.4711

0.3857

0.1230

     

0.5034

0.5034

0.7964

0.0360

0.0842

0.6054

     

19

19

21

20

21

20

     

E2CpG10

−0.3801

− 0.3801

− 0.4156

− 0.0442

− 0.0668

− 0.0898

− 0.1541

    

0.1084

0.1084

0.0610

0.8532

0.7734

0.7065

0.5050

    

19

19

21

20

21

20

21

    

E2CpG11–12

−0.4571

−0.4571

− 0.6615

0.2613

0.0946

0.2131

0.1588

0.4974

   

0.0491

0.0491

0.0011

0.2659

0.6834

0.3671

0.4918

0.0218

   

19

19

21

20

21

20

21

21

   

E2CpG13

0.1260

0.1260

0.1022

0.0637

0.2334

0.7436

0.2532

−0.0261

0.3612

  

0.6072

0.6072

0.6595

0.7896

0.3087

0.0002

0.2680

0.9106

0.1077

  

19

19

21

20

21

20

21

21

21

  

E2CpG14

0.3611

0.3611

0.0749

0.3268

0.3277

0.4237

0.3537

0.1157

0.1184

0.3634

 

0.1288

0.1288

0.7469

0.1597

0.1470

0.0627

0.1158

0.6175

0.6092

0.1054

 

19

19

21

20

21

20

21

21

21

21

 

E2CpG15–16

0.0687

0.0687

0.4151

0.2157

0.0786

0.3225

0.3674

0.1090

−0.0307

0.3456

0.3779

0.7800

0.7800

0.0613

0.3611

0.7348

0.1655

0.1013

0.6380

0.8950

0.1249

0.0912

19

19

21

20

21

20

21

21

21

21

21

E2CpG18

−0.3398

−0.3398

− 0.4726

0.0556

0.2350

−0.0527

− 0.0214

0.1926

0.2877

−0.3586

− 0.1449

0.1546

0.1546

0.0305

0.8160

0.3052

0.8255

0.9265

0.4030

0.2060

0.1104

0.5310

19

19

21

20

21

20

21

21

21

21

21

E2CpG19

0.3611

0.3611

0.0749

0.3268

0.3277

0.4237

0.3537

0.1157

0.1184

0.3634

1.0000

0.1288

0.1288

0.7469

0.1597

0.1470

0.0627

0.1158

0.6175

0.6092

0.1054

<.0001

19

19

21

20

21

20

21

21

21

21

21

PCpG2

−0.3467

−0.3467

−0.2836

0.3315

−0.1760

0.0369

0.1558

0.1069

0.2605

−0.0689

−0.0848

0.1459

0.1459

0.2129

0.1534

0.4454

0.8774

0.5002

0.6447

0.2542

0.7667

0.7149

19

19

21

20

21

20

21

21

21

21

21

PCpG3

−0.2517

−0.2517

− 0.3798

− 0.1509

0.2249

− 0.0830

− 0.1594

0.2155

0.1652

− 0.2025

− 0.0603

0.2987

0.2987

0.0895

0.5254

0.3271

0.7281

0.4900

0.3481

0.4742

0.3786

0.7953

19

19

21

20

21

20

21

21

21

21

21

PCpG4

−0.4287

−0.4287

−0.4807

−0.2412

− 0.0719

−0.3458

− 0.0344

0.4087

0.1869

−0.2648

− 0.0884

0.0670

0.0670

0.0274

0.3056

0.7566

0.1353

0.8825

0.0658

0.4172

0.2460

0.7032

19

19

21

20

21

20

21

21

21

21

21

PCpG5

−0.4217

− 0.4217

−0.6114

− 0.2451

0.1056

−0.3069

− 0.1065

0.3589

0.2236

−0.3098

− 0.2323

0.0722

0.0722

0.0032

0.2977

0.6488

0.1882

0.6460

0.1101

0.3300

0.1717

0.3108

19

19

21

20

21

20

21

21

21

21

21

PCpG6

−0.3245

− 0.3245

− 0.2233

− 0.2761

0.0764

−0.1193

− 0.2020

0.4222

0.1364

−0.0861

− 0.1235

0.2038

0.2038

0.3732

0.2833

0.7633

0.6482

0.4216

0.0809

0.5895

0.7341

0.6254

17

17

18

17

18

17

18

18

18

18

18

PCpG7

−0.3755

−0.3755

− 0.5032

− 0.2610

0.0416

− 0.2866

− 0.2846

0.3672

0.1833

− 0.3242

− 0.4005

0.1131

0.1131

0.0201

0.2663

0.8578

0.2206

0.2111

0.1015

0.4264

0.1516

0.0720

19

19

21

20

21

20

21

21

21

21

21

PCpG8

−0.3497

−0.3497

−0.5527

− 0.0989

0.1695

−0.1919

− 0.0984

0.2266

0.3144

−0.2547

− 0.2960

0.1422

0.1422

0.0094

0.6783

0.4626

0.4177

0.6714

0.3234

0.1652

0.2651

0.1926

19

19

21

20

21

20

21

21

21

21

21

PCpG9

−0.2245

− 0.2245

− 0.4057

−0.1304

0.2498

− 0.0412

− 0.1825

0.2054

0.1496

−0.1909

− 0.1361

0.3555

0.3555

0.0681

0.5838

0.2749

0.8632

0.4285

0.3719

0.5175

0.4072

0.5565

19

19

21

20

21

20

21

21

21

21

21

 

E2CpG14

E2CpG15–16

E2CpG18

E2CpG19

PCpG2

PCpG3

PCpG4

PCpG5

PCpG6

PCpG7

PCpG8

E2CpG15–16

0.3779

          

0.0912

          

21

          

E2CpG18

−0.1449

−0.0417

         

0.5310

0.8577

         

21

21

         

E2CpG19

1.0000

0.3779

−0.1449

        

<.0001

0.0912

0.5310

        

21

21

21

        

PCpG2

−0.0848

−0.2857

0.1994

−0.0848

       

0.7149

0.2094

0.3863

0.7149

       

21

21

21

21

       

PCpG3

−0.0603

−0.1634

0.5540

−0.0603

0.3050

      

0.7953

0.4792

0.0092

0.7953

0.1788

      

21

21

21

21

21

      

PCpG4

−0.0884

−0.2127

0.2790

−0.0884

0.4169

0.6760

     

0.7032

0.3547

0.2207

0.7032

0.0601

0.0008

     

21

21

21

21

21

21

     

PCpG5

−0.2323

−0.3160

0.4481

−0.2323

0.4101

0.7998

0.8982

    

0.3108

0.1628

0.0417

0.3108

0.0648

<.0001

<.0001

    

21

21

21

21

21

21

21

    

PCpG6

−0.1235

−0.0142

0.3876

−0.1235

0.1251

0.9250

0.6821

0.7313

   

0.6254

0.9555

0.1120

0.6254

0.6208

<.0001

0.0018

0.0006

   

18

18

18

18

18

18

18

18

   

PCpG7

−0.4005

−0.1929

0.5588

−0.4005

0.3459

0.7831

0.7776

0.8794

0.8090

  

0.0720

0.4022

0.0085

0.0720

0.1245

<.0001

<.0001

<.0001

<.0001

  

21

21

21

21

21

21

21

21

18

  

PCpG8

−0.2960

−0.3326

0.5817

−0.2960

0.4773

0.8641

0.6400

0.8551

0.6924

0.7911

 

0.1926

0.1407

0.0057

0.1926

0.0287

<.0001

0.0018

<.0001

0.0015

<.0001

 

21

21

21

21

21

21

21

21

18

21

 

PCpG9

−0.1361

−0.2181

0.5731

−0.1361

0.3592

0.9684

0.6016

0.7965

0.8591

0.7927

0.9092

0.5565

0.3422

0.0066

0.5565

0.1098

<.0001

0.0039

<.0001

<.0001

<.0001

<.0001

21

21

21

21

21

21

21

21

18

21

21

  1. Note: a, b, and c represent the r value, P value and the number of samples analysed for the Spearman correlation analysis, respectively