Fig. 4
From: Molecular basis of a new ovine model for human 3M syndrome-2
Partial pedigree showing segregation of the c.1716delC mutation (C = wildtype, − = deletion) with the BCRHS phenotype. The pedigree links animals in this study to three obligate carriers (animals 4, 5 and 6) and two suspected carriers (animals 1 and 8) identified in a detailed pedigree by Shariflou et al. (2011). Females and males are denoted by circles and squares, respectively. Filled symbols represent affected animals and shaded symbols represent obligate carriers. The affected animal whole genome sequenced in this study is indicated by ‘BCRHS3’