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Fig. 4 | BMC Genetics

Fig. 4

From: MCC-SP: a powerful integration method for identification of causal pathways from genetic variants to complex disease

Fig. 4

The whole network from APOE genotype to AD constructed from KEGG-based Alzheimer’s disease pathway. The hypothesis is that the APOE genetic variant can affect AD through the gene expression on Alzheimer’s disease pathway. Multiple pathways with chain structure can be formulated with the staring node APOE genotype and the end node AD. The gene and directions are highlighted with a green frame and a black arrow

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BMC Genomic Data

ISSN: 2730-6844

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