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Fig. 4 | BMC Genetics

Fig. 4

From: Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences

Fig. 4

Consurf analysis of HLA-G1. The degree of conservation of amino acids was shown in the colouring scheme. The color intensity increases based on amino acids conservation grades e.g. turquoise indicates variable sites; white indicates average sites; maroon indicates evolutionarily conserved sites. The most deleterious predicted SNPs are marked below the sequence as red arrows. e is the exposed residue. b is the buried residue. f is an estimated functional residue (highly conserved and exposed). s is an estimated structural residue (highly conserved and buried)

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