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Fig. 8 | BMC Genetics

Fig. 8

From: Type 2 diabetes susceptibility genes on mouse chromosome 11 under high sucrose environment

Fig. 8

Summary of congenic phenotype and the chromosomal segments controlling the diabetes-related traits. ↑, in C3H-11NSY mice, means significantly higher body weight and WAT weight than those in C3H mice, but not comparable to NSY mice. ↑↑, in C3H-11NSY mice, means significantly impaired glucose tolerance and insulin secretion or higher liver weight than C3H, comparable to NSY mice. ↑↑, in R2 congenic strain, means significantly impaired glucose tolerance and impaired insulin secretion than C3H mice, comparable to C3H-11NSY mice. ↑↑, in R3 and R4 congenic strains, means significantly impaired insulin secretion than C3H mice, comparable to C3H-11NSY mice. ↓, in R4 congenic strain, means significantly lower tissue weight than C3H mice. N.S. means not significant. Black bars indicate the locations of reported mouse diabetic loci

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