Haplotype (15 letters) | ‘Tag’ haplotype | AFR | EAS | EUR | SAS |
---|
AGAAGGCGAGGGGAG | GG | 0.562 | 0.86 | 0.605 | 0.642 |
GAGGCTTATAAAATA | AC | 0.209 | 0.132 | 0.172 | 0.28 |
AGGGCTTATGAAATA | GC | 0.043 | 0 | 0.21 | 0.045 |
SUM: | | 0.814 | 0.992 | 0.987 | 0.967 |
- a Supergroup denotations are given in Fig. 2. GWAS SNPs are marked with bold, eQTL causal SNP is marked in bold Cyrillic. The first allele is a major one (f > 0.5 in all supergroups), two others are minor ones. The ‘tag’ haplotype represents convoluted GWAS/eQTL 2-letter haplotype of tag SNPs (pos. 5:rs4658101, pos. 10:rs10874833). Two African–specific low frequency haplotypes AAGGCTTATGAAATA (0.099) and AAGGCTTATAAAATA (0.07) were omitted from consideration according to selection criterion