Table 2 Twenty-six downregulated genes associated with bone formation enriched in the Biological Processes found using DAVID 6.8 tool
Gene symbol | Gene ID | logFC | FDR | Gene Name |
|---|---|---|---|---|
TENM2 | ENSGALG00000001768 | −4.61 | 4.17E-05 | teneurin transmembrane protein 2 |
WFIKKN2 | ENSGALG00000007367 | −4.32 | 1.66E-06 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 |
RBP4A | ENSGALG00000006629 | −3.83 | 4.45E-09 | retinol binding protein 4 |
LECT1 | ENSGALG00000016945 | −3.19 | 3.99E-03 | chondromodulin |
COMP | ENSGALG00000003283 | −3.18 | 4.80E-02 | cartilage oligomeric matrix protein |
UCHL1 | ENSGALG00000014261 | −3.12 | 1.39E-10 | Ubiquitin C-Terminal Hydrolase L1 |
ACAN | ENSGALG00000006725 | −3.09 | 3.72E-03 | aggrecan |
CDH7 | ENSGALG00000013782 | −3.05 | 3.04E-05 | cadherin 7 |
IHH | ENSGALG00000011347 | −3.00 | 3.10E-04 | Indian hedgehog protein |
HAPLN1 | ENSGALG00000015627 | − 2.97 | 1.51E-03 | Hyaluronan and proteoglycan link protein 1 |
KIF26B | ENSGALG00000010664 | − 2.55 | 2.62E-02 | kinesin 32 Family member 26B |
PLPPR1 | ENSGALG00000015542 | −2.52 | 2.02E-05 | phospholipid phosphatase related 1 |
COL11A1 | ENSGALG00000005180 | −2.47 | 1.51E-02 | Collagen Type XI Alpha 1 Chain |
GAL3ST1 | ENSGALG00000007781 | −2.45 | 1.19E-02 | galactose-3-O-sulfotransferase 1 |
SOX9 | ENSGALG00000004386 | −2.40 | 4.58E-05 | SRY-box 9 |
SFRP1 | ENSGALG00000003473 | −2.37 | 1.47E-03 | secreted frizzled related protein 1 |
CHADL | ENSGALG00000011970 | −2.34 | 2.48E-07 | chondroadherin like |
CSGALNACT1 | ENSGALG00000010125 | −2.33 | 4.59E-06 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
FRZB | ENSGALG00000002763 | −2.33 | 1.35E-04 | frizzled-related protein |
CYR61 | ENSGALG00000008661 | −2.28 | 3.63E-07 | Protein CYR61 |
SOX8 | ENSGALG00000005263 | −2.27 | 1.29E-04 | SRY-box 8 |
THBS1 | ENSGALG00000009626 | −2.22 | 2.35E-02 | thrombospondin-1 precursor |
CHAD | ENSGALG00000019761 | −2.12 | 7.28E-03 | chondroadherin |
PDE6B | ENSGALG00000015373 | −2.11 | 1.67E-03 | phosphodiesterase 6B |
ALDH1A2 | ENSGALG00000004270 | −2.11 | 1.60E-12 | Retinal dehydrogenase 2 |
SERINC5 | ENSGALG00000014798 | −2.09 | 6.48E-05 | serine incorporator 5 |