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Table 1 Potential QTL regions for ascites syndrome based on WGR in the REL line

From: Identification and validation of quantitative trait loci for ascites syndrome in broiler chickens using whole genome resequencing

  Mbp Res-Sus SNP frequency  
Chr Start Stop Size Male Female Genes within Region
1 48.18 48.41 0.23 30% 30% APLD,GPRC5A,HEBP1,FAM234B,GSG1, EMP1,MIR6581
1 170.483 170.53 0.05 40% 0% CAB39L
1 175.68 175.87 0.19 -25% 30% PDS5B
1 182.31 182.46 0.15 40% 20% AASDHPPT,KBTBD3,MSANTD4
1 183.65 183.95 0.30 35% 35% DCUN1D5,MMP13,MMP10,MMP3,MMP7,BIRC2
2 22.86 23.03 0.17 50% 0% SAMD9L,HEPACAM2,VP50
2 34.47 34.61 0.14 40% -20% PLCL2
2 91.85 91.92 0.07 50% 0% CNDP2,FAM69C
2 95.14 95.22 0.08 -30% 0% CDH19
2 122.75 122.83 0.08 45% -25% CA2
2 126.97 127.09 0.12 40% 20% CPQ**
3 37.27 37.36 0.09 -30% 40% RYR2
3 48.98 49.00 0.02 -20% 30% RMND1
3 50.41 50.44 0.03 40% 0% SCAF8
3 100.70 101.10 0.40 0% -30% OSR1
4 36.72 36.90 0.18 40% 0% GRID2
5 13.26 13.29 0.03 0% 50% DDTNFR23, CARS
5 25.44 25.47 0.04 -50% 25% SPTBN5
6 28.82 28.87 0.05 0% 40% ABLIM1
10 6.49 6.54 0.05 40% 30% TJP1
14 1.48 1.66 0.18 0% 30% LMTK2,BHLHA15,TECPR1,BRI3,BAIAP2L1, NPTX2
20 9.06 9.10 0.04 0% -40% PXDNL,PCMTD2
22 4.40 4.48 0.08 60% 20% LRRTM4
27 7.85 7.98 0.13 -30% 0% RAMP2,WNK4,COA3,BECN1,PSME3,AOC3, G6PC,PTGES3L,RPL27,IFI35,VAT1,RND2
28 0.59 0.63 0.05 -25% 0% TIMM44,HNRNPM
Z 18.60 18.73 0.13 -25% -50% PDE4D
Z 19.10 19.50 0.40 25% 50% ZSWIM6,KIF2A
Z 33.87 33.90 0.03 25% 25% SLC24A2
  1. Regions are listed by Chromosome (Chr) and Megabase pair (Mbp) Start, Stop and Size, in the chicken genome GRCg6a assembly. Res-Sus SNP frequency is the difference in the approximate maximum frequency difference for the non-reference SNP between the phenotypes of the indicated genders. Positive Res-Sus SNP frequency difference indicates the non-reference SNPs are associated with resistance, negative values indicate association with susceptibility. **Gga2 region previously verified as a QTL [34]
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