KEGG group | KEGG subgroup | Pathway | Genes | W♀D♂ | D♀W♂ | ||
---|---|---|---|---|---|---|---|
gage | romer | gage | romer | ||||
Cellular Processes | Cell growth and death | Cell cycle | 88 | Down | Down/Mixed | Down | Down/Mixed |
Cell cycle – yeast | 54 | Down | Down/Mixed | Down | Down/Mixed | ||
Meiosis – yeast | 41 | Down | Down/Mixed | Down | Down/Mixed | ||
Environmental Information Processing | Signal transduction | ErbB signaling pathway | 40 | 2D | Down | ||
HIF-1 signaling pathway | 47 | Up | Up | ||||
MAPK signaling pathway | 110 | 2D | Up | ||||
Signaling molecules and interaction | Neuroactive ligand-receptor interaction | 112 | 2D | Up | Up/2D | Up | |
Genetic Information Processing | Folding, sorting and degradation | Proteasome | 40 | Down | Down/Mixed | Down | Down/Mixed |
Replication and repair | Base excision repair | 28 | Down | Down/Mixed | Down | Down/Mixed | |
DNA replication | 33 | Down/2D | Down/Mixed | Down/2D | Down/Mixed | ||
Homologous recombination | 20 | Down | Down/Mixed | Down | Down/Mixed | ||
Mismatch repair | 18 | Down | Down/Mixed | Down/2D | Down/Mixed | ||
Nucleotide excision repair | 35 | Down | Down/Mixed | Down | Down/Mixed | ||
Transcription | Spliceosome | 109 | Down | Down/Mixed | Down | Down/Mixed | |
Translation | Ribosome biogenesis in eukaryotes | 64 | Down | Down/Mixed | Down | Down/Mixed | |
RNA transport | 111 | Down | Down | ||||
Metabolism | Carbohydrate metabolism | Citrate cycle (TCA cycle) | 22 | Up | Up | Up | Up |
Galactose metabolism | 16 | Up | Up/Mixed | ||||
Glycolysis / Gluconeogenesis | 30 | Up | Up/Mixed | Up | Up/Mixed | ||
Starch and sucrose metabolism | 21 | Up | Up | ||||
Energy metabolism | Carbon fixation in photosynthetic organisms | 15 | Up | Up/Mixed | |||
Oxidative phosphorylation | 105 | Up | Up | Up | Up | ||
Glycan biosynthesis and metabolism | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | 11 | 2D | Up | |||
Lipid metabolism | Fatty acid degradation | 24 | Up | Up | Up | Up | |
Glycerolipid metabolism | 25 | Up | Up | ||||
Glycerophospholipid metabolism | 44 | Up | Up | ||||
Metabolism of cofactors and vitamins | One carbon pool by folate | 13 | Down | Down/Mixed | |||
Nucleotide metabolism | Purine metabolism | 104 | Down | Down/Mixed | Down | Down/Mixed | |
Pyrimidine metabolism | 73 | Down | Down/Mixed | Down | Down/Mixed | ||
Organismal Systems | Circulatory system | Cardiac muscle contraction | 41 | Up | Up/Mixed | ||
Vascular smooth muscle contraction | 55 | 2D | Up | Up/2D | Up | ||
Digestive system | Carbohydrate digestion and absorption | 15 | 2D | Up | |||
Fat digestion and absorption | 19 | Up | Up | Up | Up | ||
Gastric acid secretion | 27 | Up/2D | Up | ||||
Pancreatic secretion | 43 | Up | Up | ||||
Protein digestion and absorption | 40 | Up | Up | ||||
Vitamin digestion and absorption | 17 | Up | Up | ||||
Endocrine system | Adipocytokine signaling pathway | 35 | 2D | Up | Up/2D | Up | |
Insulin secretion | 37 | Up/2D | Up | ||||
Insulin signaling pathway | 56 | Up | Up | ||||
PPAR signaling pathway | 42 | Up | Up/Mixed | Up | Up/Mixed | ||
Environmental adaptation | Circadian rhythm | 19 | 2D | Up | |||
Immune system | T cell receptor signaling pathway | 61 | 2D | Down | |||
Nervous system | GABAergic synapse | 38 | Up | Up | |||
Glutamatergic synapse | 50 | 2D | Up | ||||
Long-term potentiation | 28 | 2D | Up | ||||
Retrograde endocannabinoid signaling | 46 | 2D | Up |