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Table 2 Association between CORIN gene polymorphisms and serum corin levels and incident hypertension

From: Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population

SNPPositionMAMAF %HWE*CorinHypertension
BetaPBeta#P #OR(95%CI)POR(95%CI)#P #
rs2289433exon 1G34.30.0750.0350.0520.0370.0401.08(0.92,1.26)0.3581.13(0.96,1.34)0.152
rs6823184intron 1C43.50.8700.0360.0330.0380.0240.95(0.82,1.11)0.5090.90(0.77,1.06)0.220
rs10008014intron 6C24.60.289−0.0020.8830.0000.9900.99(0.84,1.18)0.9311.02(0.85,1.22)0.853
rs17654423intron 6C26.60.670−0.0200.510− 0.0190.3191.02(0.87,1.20)0.8011.02(0.86,1.22)0.804
rs10517195exon 9G15.70.1670.0740.0010.0740.0020.94(0.77,1.16)0.5680.93(0.76,1.16)0.515
rs2271037intron 9T38.70.5510.0420.0220.0420.0151.01(0.87,1.17)0.9110.97(0.83,1.14)0.736
rs2351784intron 11T23.00.335−0.0140.615−0.0120.8540.92(0.77,1.10)0.3480.90(0.75,1.09)0.288
rs12509275intron 17G13.80.0640.0730.0030.0700.0041.01(0.82,1.25)0.9130.94(0.75,1.18)0.573
rs3749585exon 22C48.00.774−0.0010.814−0.0060.7370.99(0.85,1.14)0.8520.98(0.84,1.15)0.834
  1. HWE Hardy–Weinberg equilibrium; MA Minor allele; MAF Minor allele frequency
  2. *: P value for HWE using Fisher’s exact test
  3. #: Adjusted for smoking, drinking, BMI, TC, TG, HDL-C, FBG, family history of hypertension