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Table 2 Mean -log10p for not eQTL and eQTL lung cancer OncoArray SNPs. The eQTLs are stratified by tissue types

From: SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies

eQTL tissue type

non-eQTL SNP

eQTL SNP

aMW(Z)

P

-log10pb

N

-log10pb

N

Uterus

1.88/1.69

798,995

2.26/2.01

269

8.62

2.90E-17

Adipose Subcutaneous

1.88/1.69

798,297

2.04/1.83

967

7.98

5.90E-15

Vagina

1.88/1.69

798,997

2.23/1.99

267

7.95

7.60E-15

Spleen

1.88/1.69

798,688

2.13/1.9

576

7.92

9.90E-15

Prostate

1.88/1.69

798,847

2.16/1.93

417

7.78

2.80E-14

Ovary

1.88/1.69

798,916

2.18/1.95

348

7.72

4.40E-14

Cells EBV-transformed lymphocytes

1.88/1.69

798,893

2.18/1.95

371

7.69

5.90E-14

Pituitary

1.88/1.69

798,733

2.12/1.89

531

7.54

1.70E-13

Artery Coronary

1.88/1.69

798,862

2.12/1.89

402

7.54

1.80E-13

Small Intestine Terminal Ileum

1.88/1.69

798,827

2.13/1.9

437

7.41

4.60E-13

Adipose Visceral Omentum

1.88/1.69

798,503

2.07/1.85

761

7.34

8.00E-13

Brain Substantia nigra

1.88/1.69

799,078

2.26/2.01

186

7.28

1.20E-12

Whole Blood

1.88/1.69

798,578

2.09/1.87

686

7.15

3.20E-12

Brain Spinal cord cervical c-1

1.88/1.69

798,979

2.2/1.96

285

7.09

4.90E-12

Stomach

1.88/1.69

798,724

2.11/1.89

540

7.06

5.80E-12

Breast Mammary Tissue

1.88/1.69

798,703

2.1/1.88

561

7.03

7.60E-12

Brain Putamen basal ganglia

1.88/1.69

798,889

2.14/1.91

375

6.99

9.50E-12

Brain Cerebellum

1.88/1.69

798,524

2.05/1.83

740

6.99

9.80E-12

Brain Nucleus accumbens basal ganglia

1.88/1.69

798,766

2.12/1.89

498

6.96

1.20E-11

Brain Cortex

1.88/1.69

798,735

2.11/1.89

529

6.9

1.80E-11

Esophagus Gastroesophageal Junction

1.88/1.69

798,628

2.09/1.87

636

6.83

3.00E-11

Artery Tibial

1.88/1.69

798,325

2.02/1.81

939

6.78

4.20E-11

Colon Transverse

1.88/1.69

798,567

2.08/1.86

697

6.71

6.70E-11

Pancreas

1.88/1.69

798,628

2.09/1.87

636

6.7

7.30E-11

Skin Not Sun Exposed Suprapubic

1.88/1.69

798,372

2.05/1.83

892

6.66

9.30E-11

Heart Atrial Appendage

1.88/1.69

798,574

2.08/1.86

690

6.6

1.30E-10

Adrenal Gland

1.88/1.69

798,712

2.06/1.84

552

6.59

1.50E-10

Brain Cerebellar Hemisphere

1.88/1.69

798,607

2.04/1.83

657

6.51

2.50E-10

Liver

1.88/1.69

798,893

2.11/1.89

371

6.47

3.20E-10

Brain Frontal Cortex BA9

1.88/1.69

798,788

2.1/1.88

476

6.31

9.00E-10

Skin Sun Exposed Lower leg

1.88/1.69

798,261

2.04/1.83

1003

6.27

1.20E-09

Brain Hippocampus

1.88/1.69

798,936

2.14/1.91

328

6.12

3.00E-09

Heart Left Ventricle

1.88/1.69

798,640

2.07/1.85

624

6.08

3.70E-09

Thyroid

1.88/1.69

798,130

2.02/1.81

1134

5.92

9.60E-09

Lung

1.88/1.69

798,354

2.02/1.81

910

5.88

1.20E-08

Nerve Tibial

1.88/1.69

798,217

2.02/1.81

1047

5.85

1.50E-08

Esophagus Mucosa

1.88/1.69

798,316

2.03/1.82

948

5.85

1.50E-08

Minor Salivary Gland

1.88/1.69

799,032

2.14/1.91

232

5.84

1.60E-08

Artery Aorta

1.88/1.69

798,498

2.01/1.8

766

5.69

3.70E-08

Brain Caudate basal ganglia

1.88/1.69

798,771

2.04/1.83

493

5.53

9.10E-08

Colon Sigmoid

1.88/1.69

798,658

2.05/1.83

606

5.45

1.40E-07

Testis

1.88/1.69

798,195

2.01/1.8

1069

5.44

1.50E-07

Brain Hypothalamus

1.88/1.69

798,938

2.12/1.89

326

5.4

1.80E-07

Muscle Skeletal

1.88/1.69

798,409

2.02/1.81

855

5.22

4.90E-07

Cells Transformed fibroblasts

1.88/1.69

798,375

2.02/1.81

889

5.06

1.10E-06

Brain Anterior cingulate cortex BA24

1.88/1.69

798,880

2.02/1.81

384

3.91

1.90E-04

Brain Amygdala

1.88/1.69

799,022

1.98/1.78

242

2.44

2.00E-02

  1. aMW(Z) is a Z statistics from Mann-Whitney test for comparing two samples
  2. bmean/median
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