Fig. 4

The result of the dual-luciferase reporter assay for target confirmation (n = 3). a Target site for miR-148a/miR-10a in the BMP7 3’UTR and the construction of the luciferase (Luc) expression vector fused with the BMP7 3’UTR. WT and MUT represent the Luc reporter vector with the WT, and the mutation at the miR-148a/miR-10a site in the BMP7 3’UTR, respectively. b The relative luciferase activity after co-transfecting miR-148a mimic/mimic-NC and the wild type (WT) vector or the mutant vector 1 in Hu sheep dermal papilla cells. c The relative luciferase activity after co-transfecting miR-10a mimic/mimic-NC and the WT type vector or the mutant vector 2 in Hu sheep dermal papilla cells. * represents a significant difference between the experimental group and the control group. ** represents a great significant difference between the experimental group and the control group