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Table 3 Genotype and allele frequencies for rs10252701 (AHR) and rs79105258 (CUX2) according to habitual coffee consumption level

From: GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in the Japanese population

SNP Coffee consumption (Cups/day)
Allele 0.00 0.00–1.00 1.00–3.00 3.00–10.00
rs10252701 AA [N (%)] 740 (43.7) 1151 (43.4) 2481 (46.6) 1339 (52.2)
N = 12,239 CA [N (%)] 753 (44.5) 1204 (45.4) 2311 (43.4) 1010 (39.4)
CC [N (%)] 200 (11.8) 299 (11.3) 535 (10.0) 216 (8.4)
OR (95% CI) 1 (ref.) 1.00 (0.91–1.09) 0.90 (0.83–0.98) 0.76 (0.69–0.84)
P 0.92 0.01 9.1 × 10−9
rs79105258 CC [N (%)] 1015 (60.0) 1594 (60.1) 2960 (55.6) 1269 (49.5)
N = 12,239 AC [N (%)] 578 (34.1) 872 (32.9) 2040 (38.3) 1089 (42.5)
AA [N (%)] 100 (5.9) 188 (7.1) 327 (6.1) 207 (8.1)
OR (95% CI) 1 (ref.) 1.03 (0.93–1.14) 1.13 (1.04–1.24) 1.39 (1.26–1.54)
P 0.58 6.7 × 10−3 1.4 × 10−10
  1. OR Odds ratio, CI Confidence interval. All ORs and P-values were calculated by a logistic regression method with the additive genetic model