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Fig. 4 | BMC Genetics

Fig. 4

From: Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans

Fig. 4

Analyses of nonsynonymous SNPs. a Excess of heterozygosity comparison between Biobank (orange) and Wellderly (green) for SNPs with top 10% excess of heterozygosity in Biobank (left shaded area) and SNPs with top 10% excess of heterozygosity in Wellderly (right shaded area). **** P < 1e-4; ***** P < 1e-10, Mann-Whitney U test. b Evolutionary probability comparison between the top SNPs in Biobank (orange) and the tops SNPs in Wellderly (green). c CADD score comparison between the top SNPs in Biobank (orange) and the top SNPs in Wellderly (green). d Significantly enriched gene sets for genes involving the top SNPs in Biobank and genes involving the top SNPs in Wellderly

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BMC Genomic Data

ISSN: 2730-6844

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