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Table 3 Additive (a), dominant (d) and substitution (α) effects of six SNPs on milk fatty acid traits

From: A post-GWAS confirming effects of PRKG1 gene on milk fatty acids in a Chinese Holstein dairy population

SNP Genotype C6:0 C8:0 C10:0 C11:0 C12:0 C13:0 C14:0 C14:1 C15:0 C16:0 C16:1 C17:0
 g.8344262A > T a 0.0066 0.0146* −0.0054 0.0009 − 0.0014 0.0011 − 0.0195 − 0.0054 0.0046 − 0.0758 0.0341* − 0.0022
d −0.0100 − 0.0046 − 0.0842** 0.0013 − 0.0291 0.0014 − 0.1461* 0.0097 0.0021 − 0.0754 0.0546* 0.0027
α 0.0103 0.0163** 0.0259 0.0004 0.0094 0.0006 0.0344 −0.009 0.0038 −0.0480 0.0136 − 0.0032
 g.6904047G > T a −0.0291 0.0172 −0.0098 0.0021 −0.0167 0.0021 0.0712 0.0055 −0.0009 0.0257 −0.0027 0.0015
d −0.0189 0.0241 − 0.0203 0.0025 −0.0262 0.0020 −0.0952 0.0119 0.0052 0.1041 0.0655 0.0072
α −0.0169 0.0019 0.0032 0.0005 0 0.0008 0.1327* −0.0021 − 0.0042 − 0.0408 −0.0449* − 0.0031
 g.6903810G > A a 0.0288 0.0553** −0.0493 − 0.0022 − 0.0633 −0.0039 0.0752 −0.0005 − 0.0312 − 0.1919 − 0.0391 −0.007
d −0.0417* − 0.0620** − 0.0132 0.0010 0.0109 0.0016 −0.0657 0.0108 0.0367 0.3431 0.0388 0.0083
α −0.0028 0.0087 −0.0593* − 0.0015 − 0.0551 − 0.0028 0.0255 0.0076 − 0.0035 0.0686 − 0.0099 − 0.0007
 g.6903365C > A a − 0.0094 − 0.0018 0.0013 0.0005 0.0340 −0.0010 0.1488* 0.0036 0.0146 0.2369 −0.0173 0.0027
d 0.0697** 0.0564** 0.0548 0.0011 0.0443 −0.0032 0.0392 0.0147 0.0035 0.4768* 0.0681* 0.0037
α −0.0465** − 0.0305** − 0.0264 −0.0001 0.0114 0.0006 0.1288 −0.0039 0.0128 −0.0068 −0.0514 0.0009
 g.6902878 T > G a −0.0309** −0.0146** − 0.0309* −0.0018 − 0.0318 − 0.0021 − 0.0321 0.0089 − 0.0042 − 0.0211 0.0102 −0.0002
d 0.3259** 0.3817** 0.3265 −0.0018 0.0623 −0.0023 1.3282* −0.0786 − 0.0071 − 0.0482 − 0.1943 − 0.0311
α 0.0458 0.0786** 0.0492 −0.0022 −0.0168 − 0.0026 0.2943* − 0.0105 − 0.0059 − 0.0333 −0.0372 − 0.0078
 g.6901713 T > G a 0.0267 0.0674** 0.0237 −0.0020 − 0.0631 0.0013 −0.0582 − 0.0524* − 0.0012 − 0.4319* 0.0069 − 0.0006
d 0.0063 −0.0106 0.0726 0.0019 0.1192* 0.0005 0.2028* 0.0439 0.0052 0.3023 −0.0254 − 0.0056
α 0.0308** 0.0606** 0.0703** −0.0008 0.0132 0.0016 0.0710 −0.0244 0.0022 −0.2381 − 0.0094 − 0.0042
SNP Genotype C17:1 C18:0 C18:1cis-9 C18 index C20:0 C14 index C16 index C17 index SFA UFA SFA/UFA Total index
 g.8344262A > T a 0.0009 −0.0571 0.0853 0.2704 − 0.0007 − 0.0224 0.0937* 0.3620* − 0.1265 0.1493 −0.0167 0.1808
d 0.0059** −0.1113 0.4005** 0.6935** 0.0014 0.1412 0.1605** 0.4716* −0.3642* 0.3410* −0.0348 0.5566**
α −0.0013 −0.0154 − 0.0633 0.5280* − 0.0012 −0.0748 0.0333 0.1864 0.0089 0.0224 −0.0037 −0.0262
 g.6904047G > T a −0.0110** −0.1433 0.0693 0.2298 0.0013 0.1239 0.0362 −0.9301** 0.0869 −0.0400 0.0114 −0.0164
d −0.0068 −0.0639 0.0494 −0.1365 0.0063* 0.2037 0.1649 −0.7603* 0.1787 −0.0260 0.0147 −0.0462
α −0.0067** −0.1023 0.0378 0.1424 −0.0026 −0.0076 − 0.0700 −0.4462* − 0.0276 −0.0234 0.0020 0.0132
 g.6903810G > A a −0.0028 0.0705 0.1498 0.1237 −0.0031 −0.1235 − 0.0408 0.1277 − 0.1179 0.1010 − 0.0366 0.4996**
d 0.0028 0.0826 −0.3499 −0.7147 0.0090** 0.1963 0.0223 −0.0184 0.4120 −0.2937 0.0755* −0.8470**
α −0.0007 0.1328 −0.1151 0.6653 0.0038* 0.0250 −0.0239 0.1138 0.1943 −0.1214 0.0204 −0.1407
 g.6903365C > A a −0.0034 −0.0857 0.1004 0.1746 −0.0069** −0.0689 − 0.0520 −0.3239 − 0.0298 0.1709 0.0119 0.0113
d 0.0024 0.1317 −0.4709** −0.6601 − 0.0014 0.0588 0.1108 −0.0592 0.4795* −0.4906* 0.0763* −0.5279**
α −0.0046 −0.1524 0.3397* 0.5108 −0.0062** −0.0986 − 0.1073 −0.2936 − 0.2736 0.4202* − 0.0269 0.2786
 g.6902878 T > G a 0.0027 0.0885 0.1149 −0.0171 0.0013 0.0799 0.0413 0.2243 −0.1264 0.0961 −0.0127 0.0664
d −0.0568** 1.0326 −1.5381 −2.6758 0.0463* −1.4836 −0.4590 −3.1553 2.2315 −2.6279 0.3967* −2.0918
α −0.0111* 0.3384 −0.2603 0.6394 0.0150* −0.2903 −0.0694 − 0.5286 0.4180 − 0.5487 0.0854 − 0.4469
 g.6901713 T > G a −0.0070* 0.0808 0.0910 0.1641 −0.0049* −0.4826** − 0.0075 −0.1871 − 0.1409 0.1532 − 0.0158 0.1616
d −0.0023 −0.1794 − 0.3048 −0.1731 0.0041 0.2286 −0.0357 −0.4765 0.2900 −0.3594 0.0359 −0.4236*
α −0.0085** −0.0339 − 0.1048 0.2749 − 0.0023 −0.3369** − 0.0304 −0.4950** 0.0448 −0.0772 0.0072 −0.1098
  1. Note: *: P < 0.05. **: P < 0.01
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