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Fig. 1 | BMC Genetics

Fig. 1

From: Joint analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

Fig. 1

An example to show the connections between Hi-C data and eQTL results. The top triangle is the raw Hi-C contact matrix for a 12 Mb region in chromosome 9 (chr9:92,000,000-104,000,000) for the DLPFC tissue at 40Kb resolution. The bottom triangle shows a TAD (chr9:99,640,000-100,480,000), which contains a DLPFC-specific FIRE (chr9:100,320,000-100,360,000) and an eGene, XPA (xeroderma pigmentosum complementation group A; chr9:100,437,191-100,459,639). The GTEx study identified 20 eQTLs inside this FIRE for XPA in the tissue of brain frontal cortex

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