From: Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
Parameters | Label | Settings |
---|---|---|
sample size | N | 100, 200 |
number of genes in potential pathway | v | 10,20, 30 |
correlation between genes in pathway | c | 0, 0.25, 0.5 |
proportion of interaction genes | p | 0.8, 1.0 |
OR of core gene | s | 0, 1.5, 1.8, 2.0 |
OR of interactions | Â | exp(s)/2 |
OR of genes in potential pathway | Â | 1.2 |