Skip to main content

Table 2 Lead SNPs from genome-wide associated regions for protein yield in Nordic Holstein cattle. Base positions are given as position in UMD 3.1.1 [49]

From: Dissecting closely linked association signals in combination with the mammalian phenotype database can identify candidate genes in dairy cattle

BTA

base position

Imputation accuracy

Effect

–log10(p)

Region

gene

Annotation

1

63,177,947

0.9885

−1.94

12.35

62,590,679~63,428,175

ENSBTAG00000046854 (near)

intergenic

2

124,837,669

0.9886

1.59

12.63

124,587,873~125,089,732

PTPRU

intron

2

86095020a

0.9910

1.27

9.53

85,393,563~86,345,056

ANKRD44

intron

3

17,160,521

0.9717

−1.15

8.76

16,197,245~17,415,613

S100A12 (near)

upstream

4

103,211,543

0.9321

−1.06

8.74

102,341,267~103,461,820

ATP6V0A4

intron

5

93,511,826

0.8626

−1.37

14.25

93,087,740~93,762,020

LMO3 (near)

intergenic

5

21792183a

0.9813

−1.37

10.39

21,542,557~22,042,238

SNORD107 (near)

intergenic

5

87923795b

0.9926

1.50

8.97

86,950,758~88,173,798

ETNK1 (near)

intergenic

6

88,477,501

0.9962

−2.60

25.98

88,227,821~88,727,537

SLC4A4

intron

6

48,694,003a

0.9785

1.89

12.16

47,720,473~48,944,178

ENSBTAG00000045570 (near)

intergenic

6

88847595b

0.9009

−1.82

23.84

88,477,501~89,097,608

GC (near)

intergenic

7

41,372,989

0.9999

−1.54

18.14

41,085,164~41,623,965

MGAT1 (near)

intergenic

7

72100619a

0.9077

1.59

13.29

71,120,920~72,350,707

EBF1 (near)

intergenic

8

93,065,787

0.8573

1.65

10.07

92,816,321~93,315,869

GRIN3A

Intron

8

31538155a

1.0000

1.91

9.62

30,550,864~31,788,181

LURAP1L (near)

intergenic

9

33,267,855

0.8655

−1.46

11.96

32,627,954~33,518,971

SLC35F1 (near)

intergenic

10

93,933,304

0.8370

−1.36

9.90

92,933,459~94,183,400

SEL1L

intron

11

35,512,708

0.9999

−1.45

11.82

35,189,581~35,762,749

ENSBTAG00000027786 (near)

intergenic

13

37,208,792

0.9279

−1.69

10.90

36,702,834~37,459,042

MKX (near)

intergenic

14

1,835,440

0.7471

2.84

48.66

1,448,510~2,085,468

BOP1

intron

14

67981742a

0.7652

1.78

11.60

67,731,848~68,231,920

STK3

intron

16

32,262,983

0.9290

−1.52

12.79

31,268,349~32,513,084

SMYD3

intron

18

57,015,407

0.9754

2.56

17.71

56,767,474~57,265,703

POLD1

intron

18

15057077a

0.9934

1.27

9.99

14,811,219~15,308,407

VPS35

intron

19

27,522,927

0.8500

−1.42

12.55

27,156,952~27,773,922

ASGR1 (near)

intergenic

19

61014793a

0.8505

−1.08

8.65

60,313,953~61,265,218

KCNJ2 (near)

intergenic

20

69,006,609

0.9920

−1.29

11.27

68,120,719~69,256,618

IRX1 (near)

intergenic

20

8830351a

0.9433

−1.71

10.61

8,345,063~9,080,402

ENSBTAG00000012775 (near)

intergenic

23

10,974,968

0.9304

−1.18

10.68

10,234,192~11,224,969

FGD2 (near)

intergenic

25

36,403,719

1.0000

1.33

10.25

36,112,575~36,654,175

EPO (near)

intergenic

26

37,695,494

0.9122

−1.41

14.76

36,699,144~37,945,656

SHTN1 (near)

intergenic

27

36,304,978

0.9834

1.06

8.52

36,037,123~36,555,106

ANK1

intron

29

17,620,617

0.9576

1.47

10.37

16,671,270~17,870,637

NARS2

intron

29

35459126a

0.9999

1.61

10.11

34,854,011~35,709,168

NTM

intron

Total number of significant SNPs

36,644

  1. Note, aindicated this SNP was found on second round, bindicated this SNP was found on third round