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Fig. 3 | BMC Genetics

Fig. 3

From: Characterization and functional analyses of the human HTR1A gene: 5’ regulatory region modulates gene expression in vitro

Fig. 3

Relative fluorescence intensities of the 12 recombinant vectors with the 5′ end deletion in the HEK-293 cell line. There were significant differences in the relative fluorescence intensities between several fragments: − 1649 bp to + 99 bp, − 1550 bp to + 99 bp, − 1409 bp to + 99 bp and − 1381 bp to + 99 bp. There were also 2 regions with significant regulatory effects on gene expression: − 1196 bp to − 1124 bp and − 1124 bp to − 1064 bp. The relative fluorescence intensity is expressed as the mean ± standard deviation. The difference in relative fluorescence intensity between adjacent sequences was determined by the least significant difference-T test. * 0.02 < p < 0.05, ** 0.001 < p < = 0.02, *** p < = 0.001

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