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Fig. 1 | BMC Genetics

Fig. 1

From: A panel of 32 AIMs suitable for population stratification correction and global ancestry estimation in Mexican mestizos

Fig. 1

AIMs selection algorithm. Step 1 included the initial selection of 4 nested subsets of AIMs based on SNP weights of a PCA using 1.4 M of SNPs of 1953 Mexican individuals. Step 2 comprised the ancestry index computation for each nested subset of AIMs in order to evaluate its performance for population stratification. Step 3 involved the selection of the most accurate subset with the minimal number of AIMs, as well as comparing with three previously published panels. Step 4 comprised a validation to assess the accuracy of the minimal panel for population stratification correction in small samples and different regions of Mexico, as well as in a non-metabolic trait association study and global ancestry estimation

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