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Table 3 DMRs associated with the rs12150660 SHBG polymorphism

From: Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

 

Differentially methylated region (DMR)

N CpGs

Åœidak p-value

Gene

Rangea

SHBG genotype

 Childhood

  Females

Chr2:202901045–202901471

5

1.9E-03

FZD7

0.026, 0.046

  Females

Chr12:130060028–130060081

2

9.9E-03

TMEM132D

0.009, 0.018

 Adolescence

  Females

Chr11:67418045–67418406

10

7.8E-06

ACY3;SMAD3

−0.024, −0.0036

  1. aRange of effect sizes observed across CpGs comprising that DMR, where estimates are change in methylation beta per copy of rs12150660 variant allele
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BMC Genomic Data

ISSN: 2730-6844

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