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Table 4 Simulation results of hypothesis testing for three benchmark data sets. Test results of burden test and variance component test indicating the need of different mismatch probabilities setting in the models of these simulation samples

From: An improved statistical model for taxonomic assignment of metagenomics

Group

Tests

Burden Test

Variance Component Test

simLC

Long reads

0.0004

0.02

Short reads

0.131

0.009

simMC

Long reads

< 0.0001

< 0.0001

Short reads

0.002

< 0.0001

simHC

Long reads

< 0.0001

< 0.0001

Short reads

< 0.0001

< 0.0001