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Table 4 Simulation results of hypothesis testing for three benchmark data sets. Test results of burden test and variance component test indicating the need of different mismatch probabilities setting in the models of these simulation samples

From: An improved statistical model for taxonomic assignment of metagenomics

Group Tests Burden Test Variance Component Test
simLC Long reads 0.0004 0.02
Short reads 0.131 0.009
simMC Long reads < 0.0001 < 0.0001
Short reads 0.002 < 0.0001
simHC Long reads < 0.0001 < 0.0001
Short reads < 0.0001 < 0.0001