Skip to main content

Table 1 G6PD enzyme activity in the samples with G6PD Orissa, G6PD Mahidol, and G6PD Kalyan-Kerala variants

From: High resolution melting curve analysis enables rapid and reliable detection of G6PD variants in heterozygous females

Mutations

Exons

Amino acid substitution

Enzyme activity U/g Hb

Enzyme activity compared to the cut-off (%)

c.C131G*

Exon 3

p. Ala44Gly

3.10

57.93% ↓

c.C131G#

Exon 3

p. Ala44Gly

4.89

33.60% ↓

c.G487A#

Exon 6

p. Gly163Ser

7.67

03.91% ↑

c.G487A#

Exon 6

p. Gly163Ser

11.34

35.04% ↑

c.G949A#

Exon 9

p. Glu317Lys

5.45

26.03% ↓

c.G949A#

Exon 9

p. Glu317Lys

9.38

21.45% ↑

c.G949A#

Exon 9

p. Glu317Lys

10.84

33.99% ↑

  1. # indicates heterozygous variants; *indicates homozygous variants; ↓ indicates lower; ↑ indicates higher