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Table 2 Validation of the population-differentiating transcripts on B-cell lines using TLDA cards

From: Transcriptomic population markers for human population discrimination

Gene name

Fold change

p-value

U Mann Whitney/t-test*

Genes with higher expression in Chinese

UTS2**

25.77

< 0.00001

CHI3L2

1.10

0.75656

C1ORF115

1.68

0.15560

IFITM3

1.62

0.58920

PLA2G4C

1.39

0.16152

CDC42EP5

1.13

0.75656

Genes with higher expression in European

UGT2B7

did not amplify

 

CYP1B1

1.64

0.23404

MOXD1

1.64

0.17702

UGT2B17**

3.23

0.00350

SLC7A7

2.17

0.00120

S1PR4

1.47

0.0960

TBC1D4

1.19

0.08012

  1. *p-values for genes: UTS2, UGT2B17, CHI3L2 and C1orf115 which did not fulfill the requirement of normal distribution were tested using U-Mann Whitney statistics; other genes, were tested with using the t-test
  2. **Validated on blood samples (see Validation 2 section). Significant population differences (p < 0.05) are indicated in bold
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BMC Genomic Data

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