Association between MKRN3 and LIN28B polymorphisms and precocious puberty

Table 4 Multivariate logistic regression in boys

Variables	Model 1		Model 2		Model 3
Variables	Adjusted odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	P value
Body mass index (kg/m²)	0.90 (0.72–1.12)	0.349
rs2239669		0.182
TT	0.21 (0.02–2.10)		0.22 (0.22–2.22)	0.199
CT, CC	1		1
rs12441827		0.018		0.016		0.002
TT	3.95 (1.27–12.32)		4.03 (1.30–12.48)		5.33 (1.84–15.46)
TC, CC	1		1		1

The odds ratio was adjusted for body mass index, rs12441827, rs2239669, and rs6576457
Hosmer-Lemeshow goodness-of-fit test, χ² = 9.877, p = 0.274
Nagelkerke’s R² in model 1 = 0.238, model 2 = 0.223, model 3 = 0.188