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Table 1 Contributions toward association tests from the GWAS group

From: Methods and results from the genome-wide association group at GAW20

Goal Reference Phenotype Data type Statistic type
A gene-level association test Park et al. [6] Single quantitative trait Family real GOLDN genetic data Combined score based test
A haplotype based association test Zhou et al. [8] Single binary trait Case-control and trio GOLDN real genetic data Bayes factor
A gene-environment interaction test Gao et al. [7] Single quantitative or binary trait GAW20 Case-control simulated genetic data Score based test
Joint association analysis of single SNPs and DNA methylation markers Shen et al. [10] Single quantitative trait Family real GOLDN genetic and methylation data Score based test
Jointly analyzing multiple phenotypes Deng et al. [9] Multiple quantitative traits Family real GOLDN genetic data Pedigree-based USAT (pUSAT)
  1. GOLDN Genetics of Lipid Lowering Drugs and Diet Network, SNP single-nucleotide polymorphism, USAT, unified score-based association test
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